Reactome | PAK1 [cytosol]

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PAK1 [cytosol] Show undefined attributes

candidateOf	[CandidateSet:R-HSA-428475] PAK [cytosol] - Homo sapiens
catalystActivities	[CatalystActivity:445074] protein serine/threonine kinase activity of PAK1 [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-8964628] PAK1:ARHGEF6 [cytosol] - Homo sapiens [Complex:R-HSA-2029159] RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-8964619] PAK1 binds ARHGEF6 - Homo sapiens
created	[InstanceEdit:162639] Joshi-Tope, G, 2005-04-03 19:17:56
dbId	162629
displayName	PAK1 [cytosol]
endCoordinate	545
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-162629] PAK1 [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-162629] PAK1 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-162629] PAK1 [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-162629] PAK1 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-162629] PAK1 [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-XTR-162629] PAK1 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-162629] PAK1 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-DME-162629] PAK1 [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-DME-162629-2] PAK1 [cytosol] - Drosophila melanogaster [DefinedSet:R-DME-162629-3] Homologues of PAK1 [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-162629] PAK1 [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-CEL-162629-2] PAK1 [cytosol] - Caenorhabditis elegans [DefinedSet:R-CEL-162629-3] Homologues of PAK1 [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-162629] PAK1 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-162629-2] PAK1 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-162629-3] PAK1 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-162629-4] PAK1 [cytosol] - Dictyostelium discoideum [DefinedSet:R-DDI-162629-5] Homologues of PAK1 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-SPO-162629] PAK1 [cytosol] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SPO-162629-2] PAK1 [cytosol] - Schizosaccharomyces pombe [DefinedSet:R-SPO-162629-3] Homologues of PAK1 [cytosol] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SCE-162629] PAK1 [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-162629-2] PAK1 [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-162629-3] PAK1 [cytosol] - Saccharomyces cerevisiae [DefinedSet:R-SCE-162629-4] Homologues of PAK1 [cytosol] - Saccharomyces cerevisiae
maxDepth	1
memberOf	[CandidateSet:R-HSA-442619] PAK1/3, 2 [cytosol] - Homo sapiens
modified	[InstanceEdit:3132750] Wu, G, 2013-02-13
name	PAK1 p21-activated kinase
producedByEvent	[Reaction:R-HSA-2029456] RAC1 and CDC42 activate PAK1 - Homo sapiens [Reaction:R-HSA-445072] Interaction of PAK1 with Rac1-GTP - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:Q13153] UniProt:Q13153 PAK1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-162629
startCoordinate	1
updateTrackers	[UpdateTracker:9875488] Update Tracker - [EntityWithAccessionedSequence:162629] PAK1 [cytosol] - v44:[modifyEndCoordinate]

Referrals

(updatedInstance)	[UpdateTracker:9875488] Update Tracker - [EntityWithAccessionedSequence:162629] PAK1 [cytosol] - v44:[modifyEndCoordinate]
(hasMember)	[CandidateSet:R-HSA-442619] PAK1/3, 2 [cytosol] [DefinedSet:R-HSA-390765] PAK1,2,3 [cytosol]
(output)	[Reaction:R-HSA-445072] Interaction of PAK1 with Rac1-GTP [Reaction:R-HSA-2029456] RAC1 and CDC42 activate PAK1
(hasCandidate)	[CandidateSet:R-HSA-428475] PAK [cytosol]
(input)	[Reaction:R-HSA-8964619] PAK1 binds ARHGEF6
(hasComponent)	[Complex:R-HSA-8964628] PAK1:ARHGEF6 [cytosol] [Complex:R-HSA-2029159] RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] [Complex:R-HSA-445002] PAK1 dimer [cytosol]
(physicalEntity)	[CatalystActivity:445074] protein serine/threonine kinase activity of PAK1 [cytosol]

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