Reactome | PAK1,2,3 [cytosol]

Schema > DefinedSet > Entries

catalystActivities	[CatalystActivity:10791116] protein serine/threonine kinase activity of PAK1,2,3 [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-GGA-5357487] p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] - Gallus gallus
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10755805
displayName	PAK1,2,3 [cytosol]
hasMember	[EntityWithAccessionedSequence:R-GGA-162629] PAK1 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-GGA-211604] PAK2 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-GGA-428457] PAK3 [cytosol] - Gallus gallus
inDisease	false
inferredFrom	[DefinedSet:R-HSA-390765] PAK1,2,3 [cytosol] - Homo sapiens
maxDepth	2
name	PAK1,2,3
producedByEvent	[Reaction:R-GGA-389788] Activation of PAKs by RAC1 and CDC42 - Gallus gallus [Reaction:R-GGA-399930] Activation of PAK by Rac1 - Gallus gallus
schemaClass	DefinedSet
species	[Species:49591] Gallus gallus
stId	R-GGA-390765

(physicalEntity)	[CatalystActivity:10791116] protein serine/threonine kinase activity of PAK1,2,3 [cytosol]
(hasComponent)	[Complex:R-GGA-5357487] p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] [Complex:R-GGA-389782] PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] [Complex:R-GGA-399876] Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane]
(output)	[Reaction:R-GGA-389788] Activation of PAKs by RAC1 and CDC42 [Reaction:R-GGA-399930] Activation of PAK by Rac1
(activeUnit)	[CatalystActivity:10756538] protein serine/threonine kinase activity of Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane]
(inferredTo)	[DefinedSet:R-HSA-390765] PAK1,2,3 [cytosol]