Reactome | NCK binds PAK

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NCK binds PAK Show undefined attributes

authored	[InstanceEdit:425201] Akkerman, JW, 2009-06-03
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:430178] Jupe, S, 2009-08-04
dbId	430183
displayName	NCK binds PAK
edited	[InstanceEdit:445674] Jupe, S, 2009-11-03
eventOf	[Pathway:R-HSA-202433] Generation of second messenger molecules - Homo sapiens
input	[Complex:R-HSA-430188] p-SLP-76:NCK1 [cytosol] [DefinedSet:R-HSA-390765] PAK1,2,3 [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:428521] The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1 [LiteratureReference:430182] Interaction of the Nck adapter protein with p21-activated kinase (PAK1)
maxDepth	1
modified	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
name	NCK binds PAK
orthologousEvent	[Reaction:R-CFA-430183] NCK binds PAK - Canis familiaris [Reaction:R-XTR-430183] NCK binds PAK - Xenopus tropicalis [Reaction:R-DRE-430183] NCK binds PAK - Danio rerio [Reaction:R-SSC-430183] NCK binds PAK - Sus scrofa [Reaction:R-BTA-430183] NCK binds PAK - Bos taurus [Reaction:R-RNO-430183] NCK binds PAK - Rattus norvegicus [Reaction:R-MMU-430183] NCK binds PAK - Mus musculus
output	[Complex:R-HSA-430189] p-SLP-76:NCK:PAK [cytosol]
releaseDate	2009-12-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:445650] Poole, AW, 2009-11-02 [InstanceEdit:445653] Jones, ML, 2009-11-02 [InstanceEdit:445649] Harper, MT, 2009-11-02
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-430183
summation	[Summation:430177] NCK binds to PAK through its second SH3 domain. PAK interact...

Referrals

(hasEvent)

[Pathway:R-HSA-202433] Generation of second messenger molecules