Reactome | Activation of PAK by Rac1

Schema > Reaction > Entries

Activation of PAK by Rac1 Show undefined attributes

authored	[InstanceEdit:399743] Garapati, P V, 2009-03-23 09:59:28
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:399932] Garapati, P V, 2009-03-23 10:26:35
dbId	399930
displayName	Activation of PAK by Rac1
edited	[InstanceEdit:399760] Garapati, P V, 2009-03-23 10:00:07
eventOf	[Pathway:R-HSA-399954] Sema3A PAK dependent Axon repulsion - Homo sapiens
followingEvent	[Reaction:R-HSA-399939] Autophosphorylation of PAK - Homo sapiens
input	[DefinedSet:R-HSA-399856] PAK1,2,3 dimer [cytosol] [Complex:R-HSA-399872] Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:416541] Plexin signaling via off-track and rho family GTPases
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	Activation of PAK by Rac1
orthologousEvent	[Reaction:R-MMU-399930] Activation of PAK by Rac1 - Mus musculus [Reaction:R-GGA-399930] Activation of PAK by Rac1 - Gallus gallus [Reaction:R-XTR-399930] Activation of PAK by Rac1 - Xenopus tropicalis [Reaction:R-DRE-399930] Activation of PAK by Rac1 - Danio rerio [Reaction:R-SSC-399930] Activation of PAK by Rac1 - Sus scrofa [Reaction:R-BTA-399930] Activation of PAK by Rac1 - Bos taurus [Reaction:R-CFA-399930] Activation of PAK by Rac1 - Canis familiaris [Reaction:R-RNO-399930] Activation of PAK by Rac1 - Rattus norvegicus
output	[DefinedSet:R-HSA-390765] PAK1,2,3 [cytosol] [Complex:R-HSA-399876] Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane]
releaseDate	2009-09-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:434621] Kumanogoh, A, Kikutani, H, 2009-09-01
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-399930
summation	[Summation:416538] Plexin-bound Rac1 binds to and stimulates the kinase activit...

Referrals

(hasEvent)	[Pathway:R-HSA-399954] Sema3A PAK dependent Axon repulsion
(precedingEvent)	[Reaction:R-HSA-399939] Autophosphorylation of PAK