Reactome | Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA

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Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA Show undefined attributes

authored	[InstanceEdit:398115] D'Eustachio, P, 2009-03-16 18:50:14
catalystActivity	[CatalystActivity:191973] alpha-methylacyl-CoA racemase activity of AMACR [peroxisomal matrix]
catalystActivityReference	[CatalystActivityReference:9914038] alpha-methylacyl-CoA racemase activity of AMACR [peroxisomal matrix] Purification and characterization of an alpha-methylacyl-CoA racemase from human liver
category	transition
compartment	[Compartment:17951] peroxisomal matrix
created	[InstanceEdit:389895] D'Eustachio, P, 2009-01-19 22:23:09
crossReference	[DatabaseIdentifier:9914049] RHEA:40448
dbId	389897
displayName	Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA
edited	[InstanceEdit:398202] D'Eustachio, P, 2009-03-18 13:33:40
eventOf	[Pathway:R-HSA-389887] Beta-oxidation of pristanoyl-CoA - Homo sapiens
followingEvent	[Reaction:R-HSA-389891] (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) - Homo sapiens [Reaction:R-HSA-389889] ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA - Homo sapiens
input	[SimpleEntity:R-ALL-389569] (2R) Pristanoyl-CoA [peroxisomal matrix]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:192112] Purification and characterization of an alpha-methylacyl-CoA racemase from human liver [LiteratureReference:192185] Mitochondrial and peroxisomal targeting of 2-methylacyl-CoA racemase in humans [LiteratureReference:389890] Subcellular localization and physiological role of alpha-methylacyl-CoA racemase
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA (2R)-pristanoyl-CoA => (2S)-pristanoyl-CoA
orthologousEvent	[Reaction:R-CEL-389897] Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA - Caenorhabditis elegans [Reaction:R-DME-389897] Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA - Drosophila melanogaster [Reaction:R-GGA-389897] Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA - Gallus gallus [Reaction:R-XTR-389897] Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA - Xenopus tropicalis [Reaction:R-DRE-389897] Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA - Danio rerio [Reaction:R-BTA-389897] Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA - Bos taurus [Reaction:R-RNO-389897] Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA - Rattus norvegicus [Reaction:R-MMU-389897] Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA - Mus musculus
output	[SimpleEntity:R-ALL-389893] (2S) Pristanoyl-CoA [peroxisomal matrix]
precedingEvent	[Reaction:R-HSA-389632] pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate - Homo sapiens
releaseDate	2009-04-01
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:392190] Jassal, Bijay, 2009-02-27
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-389897
summation	[Summation:389892] Peroxisomal 2-methylacyl-CoA racemase (AMACR) catalyzes the ...

Referrals

(hasEvent)	[Pathway:R-HSA-389887] Beta-oxidation of pristanoyl-CoA
(precedingEvent)	[Reaction:R-HSA-389891] (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) [Reaction:R-HSA-389889] ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA