Reactome | Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA

Schema > Reaction > Entries

Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA Show undefined attributes

catalystActivity	[CatalystActivity:10926745] alpha-methylacyl-CoA racemase activity of AMACR [peroxisomal matrix]
category	transition
compartment	[Compartment:17951] peroxisomal matrix
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10934846
displayName	Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA
eventOf	[Pathway:R-CEL-389887] Beta-oxidation of pristanoyl-CoA - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-389891] (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) - Caenorhabditis elegans [Reaction:R-CEL-389889] ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-389897] Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA - Homo sapiens
input	[SimpleEntity:R-ALL-389569] (2R) Pristanoyl-CoA [peroxisomal matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA (2R)-pristanoyl-CoA => (2S)-pristanoyl-CoA
output	[SimpleEntity:R-ALL-389893] (2S) Pristanoyl-CoA [peroxisomal matrix]
precedingEvent	[Reaction:R-CEL-389632] pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate - Caenorhabditis elegans
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-389897
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-389887] Beta-oxidation of pristanoyl-CoA
(precedingEvent)	[Reaction:R-CEL-389891] (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) [Reaction:R-CEL-389889] ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA
(inferredTo)	[Reaction:R-HSA-389897] Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA

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