Reactome | (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3)

Schema > Reaction > Entries

(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) Show undefined attributes

authored	[InstanceEdit:398115] D'Eustachio, P, 2009-03-16 18:50:14
catalystActivity	[CatalystActivity:389903] pristanoyl-CoA oxidase activity of ACOX3:FAD [peroxisomal matrix]
catalystActivityReference	[CatalystActivityReference:9914017] pristanoyl-CoA oxidase activity of ACOX3:FAD [peroxisomal matrix] Evidence for the existence of a pristanoyl-CoA oxidase gene in man
category	transition
compartment	[Compartment:17951] peroxisomal matrix
created	[InstanceEdit:389895] D'Eustachio, P, 2009-01-19 22:23:09
crossReference	[DatabaseIdentifier:12667728] RHEA:40460 [DatabaseIdentifier:9914026] RHEA:40460
dbId	389891
displayName	(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3)
edited	[InstanceEdit:398202] D'Eustachio, P, 2009-03-18 13:33:40
eventOf	[Pathway:R-HSA-389887] Beta-oxidation of pristanoyl-CoA - Homo sapiens
followingEvent	[Reaction:R-HSA-389986] trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA - Homo sapiens
input	[SimpleEntity:R-ALL-389893] (2S) Pristanoyl-CoA [peroxisomal matrix] [SimpleEntity:R-ALL-113535] O2 [peroxisomal matrix]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:389882] Peroxisomal branched chain fatty acid beta-oxidation pathway is upregulated in prostate cancer [LiteratureReference:389902] Evidence for the existence of a pristanoyl-CoA oxidase gene in man
maxDepth	1
modified	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name	(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) (2S)-pristanoyl-CoA + O2 => (2E)-pristenoyl-CoA + H2O2
orthologousEvent	[Reaction:R-DDI-389891] (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) - Dictyostelium discoideum [Reaction:R-CEL-389891] (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) - Caenorhabditis elegans [Reaction:R-DME-389891] (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) - Drosophila melanogaster [Reaction:R-GGA-389891] (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) - Gallus gallus [Reaction:R-XTR-389891] (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) - Xenopus tropicalis [Reaction:R-DRE-389891] (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) - Danio rerio [Reaction:R-SSC-389891] (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) - Sus scrofa [Reaction:R-BTA-389891] (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) - Bos taurus [Reaction:R-CFA-389891] (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) - Canis familiaris [Reaction:R-RNO-389891] (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) - Rattus norvegicus [Reaction:R-MMU-389891] (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) - Mus musculus
output	[SimpleEntity:R-ALL-113575] H2O2 [peroxisomal matrix] [SimpleEntity:R-ALL-389894] trans-2,3-dehydropristanoyl-CoA [peroxisomal matrix]
precedingEvent	[Reaction:R-HSA-389897] Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA - Homo sapiens
releaseDate	2009-04-01
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:392190] Jassal, Bijay, 2009-02-27
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-389891
summation	[Summation:389896] Peroxisomal ACOX3 catalyzes the reaction of (2S)-pristanoyl-...

Referrals

(hasEvent)	[Pathway:R-HSA-389887] Beta-oxidation of pristanoyl-CoA
(precedingEvent)	[Reaction:R-HSA-389986] trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA