Reactome | (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3)

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(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) Show undefined attributes

catalystActivity	[CatalystActivity:10755851] pristanoyl-CoA oxidase activity of ACOX3:FAD [peroxisomal matrix]
category	transition
compartment	[Compartment:17951] peroxisomal matrix
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10755853
displayName	(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3)
eventOf	[Pathway:R-GGA-389887] Beta-oxidation of pristanoyl-CoA - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-389986] trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA - Gallus gallus
inferredFrom	[Reaction:R-HSA-389891] (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) - Homo sapiens
input	[SimpleEntity:R-ALL-389893] (2S) Pristanoyl-CoA [peroxisomal matrix] [SimpleEntity:R-ALL-113535] O2 [peroxisomal matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) (2S)-pristanoyl-CoA + O2 => (2E)-pristenoyl-CoA + H2O2
output	[SimpleEntity:R-ALL-113575] H2O2 [peroxisomal matrix] [SimpleEntity:R-ALL-389894] trans-2,3-dehydropristanoyl-CoA [peroxisomal matrix]
precedingEvent	[Reaction:R-GGA-389897] Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-389891
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-389887] Beta-oxidation of pristanoyl-CoA
(precedingEvent)	[Reaction:R-GGA-389986] trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA
(inferredTo)	[Reaction:R-HSA-389891] (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3)

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