Reactome | ABCG1-mediated transport of intracellular cholesterol to the cell surface

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ABCG1-mediated transport of intracellular cholesterol to the cell surface Show undefined attributes

authored	[InstanceEdit:349660] D'Eustachio, P, 2008-05-12 17:46:52
catalystActivity	[CatalystActivity:266084] cholesterol transfer activity of ABCG1 dimer [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:13946] transport vesicle membrane
created	[InstanceEdit:266085] D'Eustachio, P, 2008-04-22 00:31:09
dbId	266082
displayName	ABCG1-mediated transport of intracellular cholesterol to the cell surface
edited	[InstanceEdit:353690] D'Eustachio, P, 2008-06-13 14:03:50
eventOf	[Pathway:R-HSA-8964058] HDL remodeling - Homo sapiens [Pathway:R-HSA-1369062] ABC transporters in lipid homeostasis - Homo sapiens
followingEvent	[Reaction:R-HSA-266299] Spherical HDL binds membrane-associated free cholesterol and phospholipids - Homo sapiens [Reaction:R-HSA-266089] Discoidal HDL binds membrane-associated free cholesterol - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-216762] CHOL [transport vesicle membrane] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:266086] ABCG1 redistributes cellular cholesterol to domains removable by high density lipoproteins but not by lipid-depleted lipoproteins
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	ABCG1-mediated transport of intracellular cholesterol to the cell surface
orthologousEvent	[Reaction:R-PFA-266082] ABCG1-mediated transport of intracellular cholesterol to the cell surface - Plasmodium falciparum [Reaction:R-DDI-266082] ABCG1-mediated transport of intracellular cholesterol to the cell surface - Dictyostelium discoideum [Reaction:R-DME-266082] ABCG1-mediated transport of intracellular cholesterol to the cell surface - Drosophila melanogaster [Reaction:R-GGA-266082] ABCG1-mediated transport of intracellular cholesterol to the cell surface - Gallus gallus [Reaction:R-XTR-266082] ABCG1-mediated transport of intracellular cholesterol to the cell surface - Xenopus tropicalis [Reaction:R-DRE-266082] ABCG1-mediated transport of intracellular cholesterol to the cell surface - Danio rerio [Reaction:R-SSC-266082] ABCG1-mediated transport of intracellular cholesterol to the cell surface - Sus scrofa [Reaction:R-BTA-266082] ABCG1-mediated transport of intracellular cholesterol to the cell surface - Bos taurus [Reaction:R-CFA-266082] ABCG1-mediated transport of intracellular cholesterol to the cell surface - Canis familiaris [Reaction:R-RNO-266082] ABCG1-mediated transport of intracellular cholesterol to the cell surface - Rattus norvegicus [Reaction:R-MMU-266082] ABCG1-mediated transport of intracellular cholesterol to the cell surface - Mus musculus
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-171095] CHOL [plasma membrane] [SimpleEntity:R-ALL-29372] Pi [cytosol]
releaseDate	2008-06-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:353689] Jassal, Bijay, 2008-06-13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-266082
summation	[Summation:266087] In an ATP-dependent reaction, ABCG1 mediates the movement of...
updateTrackers	[UpdateTracker:9790137] Update Tracker - [Reaction:266082] ABCG1-mediated transport of intracellular cholesterol to the cell surface - v35:[addInput]

Referrals

(updatedInstance)	[UpdateTracker:9790137] Update Tracker - [Reaction:266082] ABCG1-mediated transport of intracellular cholesterol to the cell surface - v35:[addInput]
(precedingEvent)	[Reaction:R-HSA-266299] Spherical HDL binds membrane-associated free cholesterol and phospholipids [Reaction:R-HSA-266089] Discoidal HDL binds membrane-associated free cholesterol
(hasEvent)	[Pathway:R-HSA-8964058] HDL remodeling [Pathway:R-HSA-1369062] ABC transporters in lipid homeostasis

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