Reactome | Spherical HDL binds membrane-associated free cholesterol and phospholipids

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Spherical HDL binds membrane-associated free cholesterol and phospholipids Show undefined attributes

authored	[InstanceEdit:349660] D'Eustachio, P, 2008-05-12 17:46:52
category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:266306] D'Eustachio, P, 2008-05-05 13:00:53
dbId	266299
displayName	Spherical HDL binds membrane-associated free cholesterol and phospholipids
edited	[InstanceEdit:353690] D'Eustachio, P, 2008-06-13 14:03:50
eventOf	[Pathway:R-HSA-8964058] HDL remodeling - Homo sapiens
input	2 × [SimpleEntity:R-ALL-171095] CHOL [plasma membrane] 2 × [SimpleEntity:R-ALL-171142] PL [plasma membrane] [Complex:R-HSA-265523] spherical HDL [extracellular region]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:266300] Phospholipid transfer protein interacts with and stabilizes ATP-binding cassette transporter A1 and enhances cholesterol efflux from cells
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	Spherical HDL binds membrane-associated free cholesterol and phospholipids
orthologousEvent	[Reaction:R-GGA-266299] Spherical HDL binds membrane-associated free cholesterol and phospholipids - Gallus gallus [Reaction:R-XTR-266299] Spherical HDL binds membrane-associated free cholesterol and phospholipids - Xenopus tropicalis [Reaction:R-DRE-266299] Spherical HDL binds membrane-associated free cholesterol and phospholipids - Danio rerio [Reaction:R-SSC-266299] Spherical HDL binds membrane-associated free cholesterol and phospholipids - Sus scrofa [Reaction:R-BTA-266299] Spherical HDL binds membrane-associated free cholesterol and phospholipids - Bos taurus [Reaction:R-CFA-266299] Spherical HDL binds membrane-associated free cholesterol and phospholipids - Canis familiaris [Reaction:R-RNO-266299] Spherical HDL binds membrane-associated free cholesterol and phospholipids - Rattus norvegicus [Reaction:R-MMU-266299] Spherical HDL binds membrane-associated free cholesterol and phospholipids - Mus musculus
output	[Complex:R-HSA-8855688] enlarged spherical HDL [extracellular region]
precedingEvent	[Reaction:R-HSA-266082] ABCG1-mediated transport of intracellular cholesterol to the cell surface - Homo sapiens
regulatedBy	[PositiveRegulation:R-HSA-266320] Positive regulation by 'PLTP [extracellular region]'
releaseDate	2008-06-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:353689] Jassal, Bijay, 2008-06-13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-266299
summation	[Summation:266301] Spherical (mature) HDL particles can acquire additional mole...
updateTrackers	[UpdateTracker:9783521] Update Tracker - [Reaction:266299] Spherical HDL binds membrane-associated free cholesterol and phospholipids - v56:[add_removeOutput, modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9783521] Update Tracker - [Reaction:266299] Spherical HDL binds membrane-associated free cholesterol and phospholipids - v56:[add_removeOutput, modifyText]
(hasEvent)	[Pathway:R-HSA-8964058] HDL remodeling