Reactome | ABCG1-mediated transport of intracellular cholesterol to the cell surface

Schema > Reaction > Entries

ABCG1-mediated transport of intracellular cholesterol to the cell surface Show undefined attributes

catalystActivity	[CatalystActivity:10227000] cholesterol transfer activity of ABCG1 dimer [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:13946] transport vesicle membrane
created	[InstanceEdit:10203599] Wright, Adam, 2024-03-07
dbId	10227002
displayName	ABCG1-mediated transport of intracellular cholesterol to the cell surface
eventOf	[Pathway:R-BTA-8964058] HDL remodeling - Bos taurus [Pathway:R-BTA-1369062] ABC transporters in lipid homeostasis - Bos taurus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-266299] Spherical HDL binds membrane-associated free cholesterol and phospholipids - Bos taurus [Reaction:R-BTA-266089] Discoidal HDL binds membrane-associated free cholesterol - Bos taurus
inferredFrom	[Reaction:R-HSA-266082] ABCG1-mediated transport of intracellular cholesterol to the cell surface - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-216762] CHOL [transport vesicle membrane] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
name	ABCG1-mediated transport of intracellular cholesterol to the cell surface
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-171095] CHOL [plasma membrane] [SimpleEntity:R-ALL-29372] Pi [cytosol]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-266082
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-8964058] HDL remodeling [Pathway:R-BTA-1369062] ABC transporters in lipid homeostasis
(precedingEvent)	[Reaction:R-BTA-266299] Spherical HDL binds membrane-associated free cholesterol and phospholipids [Reaction:R-BTA-266089] Discoidal HDL binds membrane-associated free cholesterol
(inferredTo)	[Reaction:R-HSA-266082] ABCG1-mediated transport of intracellular cholesterol to the cell surface