NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD

authored
catalystActivity
catalystActivityReference [CatalystActivityReference:9643710] nicotinate-nucleotide adenylyltransferase activity of NMNAT2:Mg2+ [Golgi membrane] Identification of a novel human nicotinamide mononucleotide adenylyltransferase
category transition
compartment
created [InstanceEdit:197203] Jassal, B, 2007-05-02 09:36:52
crossReference
dbId 197235
displayName NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD
edited
eventOf
followingEvent
goBiologicalProcess [GO_BiologicalProcess:262876] 'de novo' NAD+ biosynthetic process from L-tryptophan
input
isInDisease false
isInferred false
literatureReference
maxDepth 1
modified [InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name
  • NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD
  • nicotinate beta-D-ribonucleotide + ATP + H(+) => deamido-NAD(+) + diphosphate
  • Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT2]
orthologousEvent
output
precedingEvent
previousReviewStatus [ReviewStatus:9821385] four stars
releaseDate 2006-01-23
reviewStatus [ReviewStatus:9821382] five stars
reviewed
revised
schemaClass Reaction
species
stId R-HSA-197235
summation
updateTrackers
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