Reactome | VAV1 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

VAV1 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9029096] GRB2-1:VAV1 [cytosol] - Homo sapiens [Complex:R-HSA-389334] VAV1:PIP3:CD28:GRB2 [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-879914] IL3 stimulation induces Vav binding to Tec kinase - Homo sapiens [Reaction:R-HSA-912727] CBL binds VAV - Homo sapiens [Reaction:R-NUL-437945] Pig Syk binds human Vav1 - Sus scrofa [Reaction:R-HSA-1433542] Phosphorylation and activation of VAV1 - Homo sapiens [Reaction:R-HSA-389352] Translocation of Vav1 to CD28 - Homo sapiens [Reaction:R-HSA-9606151] Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 - Homo sapiens
created	[InstanceEdit:195029] Gopinathrao, G, 2007-04-02 17:19:01
dbId	195066
displayName	VAV1 [cytosol]
endCoordinate	845
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-434625] Vav1 [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-195066] Vav1 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-195066] VAV1 [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-195066] VAV1 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-195066] VAV1 [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-XTR-195066] vav1 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-195066] LOC107050724 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-DME-195066] Vav [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-195066] vav-1 [cytosol] - Caenorhabditis elegans
maxDepth	1
memberOf	[CandidateSet:R-HSA-442295] VAV family [cytosol] - Homo sapiens [CandidateSet:R-HSA-194849] GEFs [cytosol] - Homo sapiens [CandidateSet:R-HSA-9014432] RHOG GEFs [cytosol] - Homo sapiens [CandidateSet:R-HSA-9014398] RAC2 GEFs [cytosol] - Homo sapiens [CandidateSet:R-HSA-9013168] RAC1 GEFs [cytosol] - Homo sapiens [CandidateSet:R-HSA-8980694] RHOA GEFs [cytosol] - Homo sapiens
modified	[InstanceEdit:3132750] Wu, G, 2013-02-13
name	VAV1
referenceEntity	[ReferenceGeneProduct:uniprot:P15498] UniProt:P15498 VAV1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-195066
startCoordinate	1
updateTrackers	[UpdateTracker:9868316] Update Tracker - [EntityWithAccessionedSequence:195066] VAV1 [cytosol] - v30:[modifyName] [UpdateTracker:9876294] Update Tracker - [EntityWithAccessionedSequence:195066] VAV1 [cytosol] - v44:[modifyEndCoordinate]

Referrals

(updatedInstance)	[UpdateTracker:9868316] Update Tracker - [EntityWithAccessionedSequence:195066] VAV1 [cytosol] - v30:[modifyName] [UpdateTracker:9876294] Update Tracker - [EntityWithAccessionedSequence:195066] VAV1 [cytosol] - v44:[modifyEndCoordinate]
(hasComponent)	[Complex:R-HSA-9029096] GRB2-1:VAV1 [cytosol] [Complex:R-HSA-912729] TEC:VAV1 [cytosol] [Complex:R-HSA-912755] p(Y700,731,774)-CBL:VAV1 [cytosol] [Complex:R-HSA-389334] VAV1:PIP3:CD28:GRB2 [plasma membrane] [Complex:R-NUL-446294] Syk:VAV1 [cytosol] [Complex:R-HSA-9606167] Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:BTK:NCK1:VAV1:PLCG2 [plasma membrane] [Complex:R-HSA-9606149] Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:p-Y551-BTK:NCK1:VAV1:PLCG2 [plasma membrane] [Complex:R-HSA-9606153] Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:p-Y223,Y551-BTK:NCK1:VAV1:PLCG2 [plasma membrane]
(hasMember)	[CandidateSet:R-HSA-8980694] RHOA GEFs [cytosol] [CandidateSet:R-HSA-9014398] RAC2 GEFs [cytosol] [CandidateSet:R-HSA-9013168] RAC1 GEFs [cytosol] [CandidateSet:R-HSA-9014432] RHOG GEFs [cytosol] [CandidateSet:R-HSA-194849] GEFs [cytosol] [CandidateSet:R-HSA-442295] VAV family [cytosol] [DefinedSet:R-HSA-430172] VAV1,2,3 [cytosol]
(input)	[Reaction:R-HSA-1433542] Phosphorylation and activation of VAV1 [Reaction:R-HSA-879914] IL3 stimulation induces Vav binding to Tec kinase [Reaction:R-HSA-912727] CBL binds VAV [Reaction:R-HSA-389352] Translocation of Vav1 to CD28 [Reaction:R-NUL-437945] Pig Syk binds human Vav1 [Reaction:R-HSA-9606151] Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1

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