Reactome | COMT transfer CH3 from AdoMet to 3,4DHBNZ

Schema > Reaction > Entries

COMT transfer CH3 from AdoMet to 3,4DHBNZ Show undefined attributes

catalystActivity	[CatalystActivity:175988] catechol O-methyltransferase activity of COMT [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:175984] Jassal, B, 2006-02-27 14:53:40
dbId	175983
displayName	COMT transfer CH3 from AdoMet to 3,4DHBNZ
eventOf	[Pathway:R-HSA-156581] Methylation - Homo sapiens
followingEvent	[Reaction:R-HSA-174401] AHCY:NAD+ tetramer hydrolyses AdoHcy - Homo sapiens
input	[SimpleEntity:R-ALL-175977] 3,4DHBNZ [cytosol] [SimpleEntity:R-ALL-71284] AdoMet [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:200732] Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders
maxDepth	1
modified	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
name	COMT transfer CH3 from AdoMet to 3,4DHBNZ 3,4-dihydroxybenzoate can be O-methylated
orthologousEvent	[Reaction:R-MMU-175983] COMT transfer CH3 from AdoMet to 3,4DHBNZ - Mus musculus [Reaction:R-CFA-175983] COMT transfer CH3 from AdoMet to 3,4DHBNZ - Canis familiaris [Reaction:R-SPO-175983] COMT transfer CH3 from AdoMet to 3,4DHBNZ - Schizosaccharomyces pombe [Reaction:R-XTR-175983] COMT transfer CH3 from AdoMet to 3,4DHBNZ - Xenopus tropicalis [Reaction:R-BTA-175983] COMT transfer CH3 from AdoMet to 3,4DHBNZ - Bos taurus [Reaction:R-GGA-175983] COMT transfer CH3 from AdoMet to 3,4DHBNZ - Gallus gallus [Reaction:R-DRE-175983] COMT transfer CH3 from AdoMet to 3,4DHBNZ - Danio rerio [Reaction:R-SSC-175983] COMT transfer CH3 from AdoMet to 3,4DHBNZ - Sus scrofa [Reaction:R-RNO-175983] COMT transfer CH3 from AdoMet to 3,4DHBNZ - Rattus norvegicus
output	[SimpleEntity:R-ALL-175978] 3H,4MBNZ [cytosol] [SimpleEntity:R-ALL-71285] AdoHcy [cytosol]
precedingEvent	[Reaction:R-HSA-174391] MAT1A multimers transfer Ado from ATP to L-Met - Homo sapiens [Reaction:R-HSA-5603114] MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met - Homo sapiens
releaseDate	2005-04-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:351775] D'Eustachio, P, 2008-05-28 08:30:54
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-175983
summation	[Summation:176091] Dihydroxybenzoate is a typical substrate for Catechol O-meth...
updateTrackers	[UpdateTracker:9792140] Update Tracker - [Reaction:175983] COMT transfer CH3 from AdoMet to 3,4DHBNZ - v23:[addLiteratureReference]

Referrals

(updatedInstance)	[UpdateTracker:9792140] Update Tracker - [Reaction:175983] COMT transfer CH3 from AdoMet to 3,4DHBNZ - v23:[addLiteratureReference]
(hasEvent)	[Pathway:R-HSA-156581] Methylation
(precedingEvent)	[Reaction:R-HSA-174401] AHCY:NAD+ tetramer hydrolyses AdoHcy