Reactome | COMT transfer CH3 from AdoMet to 3,4DHBNZ

Schema > Reaction > Entries

COMT transfer CH3 from AdoMet to 3,4DHBNZ Show undefined attributes

catalystActivity	[CatalystActivity:10571826] catechol O-methyltransferase activity of COMT [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10571828
displayName	COMT transfer CH3 from AdoMet to 3,4DHBNZ
eventOf	[Pathway:R-DRE-156581] Methylation - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-174401] AHCY:NAD+ tetramer hydrolyses AdoHcy - Danio rerio
inferredFrom	[Reaction:R-HSA-175983] COMT transfer CH3 from AdoMet to 3,4DHBNZ - Homo sapiens
input	[SimpleEntity:R-ALL-175977] 3,4DHBNZ [cytosol] [SimpleEntity:R-ALL-71284] AdoMet [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	COMT transfer CH3 from AdoMet to 3,4DHBNZ 3,4-dihydroxybenzoate can be O-methylated
output	[SimpleEntity:R-ALL-175978] 3H,4MBNZ [cytosol] [SimpleEntity:R-ALL-71285] AdoHcy [cytosol]
precedingEvent	[Reaction:R-DRE-174391] MAT1A multimers transfer Ado from ATP to L-Met - Danio rerio [Reaction:R-DRE-5603114] MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-175983
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-156581] Methylation
(precedingEvent)	[Reaction:R-DRE-174401] AHCY:NAD+ tetramer hydrolyses AdoHcy
(inferredTo)	[Reaction:R-HSA-175983] COMT transfer CH3 from AdoMet to 3,4DHBNZ

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