Reactome | Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer.

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Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer. Show undefined attributes

authored	[InstanceEdit:168344] Luo, F, 2005-11-16 12:05:41
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:168513] Gillespie, ME, 2005-11-17 05:52:23
dbId	168440
displayName	Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer.
edited	[InstanceEdit:450361] Shamovsky, V, 2009-12-16
eventOf	[Pathway:R-HSA-450341] Activation of the AP-1 family of transcription factors - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-450237] p-S63,S73-JUN [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-450243] p-T69,T71-ATF2 [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:169947] Regulatory mechanisms involved in activator-protein-1 (AP-1)-mediated activation of glutathione-S-transferase gene expression by chemical agents
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer.
orthologousEvent	[Reaction:R-SCE-168440] Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer. - Saccharomyces cerevisiae [Reaction:R-GGA-168440] Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer. - Gallus gallus [Reaction:R-DRE-168440] Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer. - Danio rerio [Reaction:R-SSC-168440] Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer. - Sus scrofa [Reaction:R-BTA-168440] Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer. - Bos taurus [Reaction:R-CFA-168440] Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer. - Canis familiaris [Reaction:R-RNO-168440] Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer. - Rattus norvegicus [Reaction:R-MMU-168440] Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer. - Mus musculus
output	[Complex:R-HSA-450262] p-2S-cJUN:p-2T-ATF2 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-168136] Activated JNKs phosphorylate c-JUN - Homo sapiens [Reaction:R-HSA-168053] Phosphorylated MAPKs phosphorylate ATF-2 - Homo sapiens
releaseDate	2010-03-16
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:188961] Gay, NJ, 2006-04-24 16:48:17
revised	[InstanceEdit:450323] Shamovsky, V, 2009-12-16
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-168440
summation	[Summation:178671] At the beginning of this reaction, 1 molecule of 'c-Jun-P', ...
updateTrackers	[UpdateTracker:9791053] Update Tracker - [Reaction:168440] Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer. - v32:[add_removeInput, add_removeOutput]

Referrals

(updatedInstance)	[UpdateTracker:9791053] Update Tracker - [Reaction:168440] Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer. - v32:[add_removeInput, add_removeOutput]
(hasEvent)	[Pathway:R-HSA-450341] Activation of the AP-1 family of transcription factors