Reactome | Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer.

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Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer. Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10459488
displayName	Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer.
eventOf	[Pathway:R-SSC-450341] Activation of the AP-1 family of transcription factors - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-168440] Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer. - Homo sapiens
input	[EntityWithAccessionedSequence:R-SSC-450243] phospho-ATF2 [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-450237] phospho-JUN [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer.
output	[Complex:R-SSC-450262] p-2S-cJUN:p-2T-ATF2 [nucleoplasm]
precedingEvent	[Reaction:R-SSC-168136] Activated JNKs phosphorylate c-JUN - Sus scrofa [Reaction:R-SSC-168053] Phosphorylated MAPKs phosphorylate ATF-2 - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-168440
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-450341] Activation of the AP-1 family of transcription factors
(inferredTo)	[Reaction:R-HSA-168440] Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer.

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