Reactome | p-S63,S73-JUN [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

p-S63,S73-JUN [nucleoplasm] Show undefined attributes

authored	[InstanceEdit:167907] Luo, F, 2005-11-10 11:23:18
compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-450327] p-2S-cJUN:p-2S,2T-cFOS [nucleoplasm] - Homo sapiens [Complex:R-HSA-450262] p-2S-cJUN:p-2T-ATF2 [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-168440] Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer. - Homo sapiens [Reaction:R-HSA-450292] Formation of Activated Protein 1 (AP-1) complex. cFOS/c-JUN heterodimer. - Homo sapiens
created	[InstanceEdit:450323] Shamovsky, V, 2009-12-16
dbId	450237
displayName	p-S63,S73-JUN [nucleoplasm]
endCoordinate	331
hasModifiedResidue	[ModifiedResidue:168361] O-phospho-L-serine at 63 [ModifiedResidue:450265] O-phospho-L-serine at 73
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-450237] phospho-Jun [nucleoplasm] - Mus musculus [EntityWithAccessionedSequence:R-RNO-450237] phospho-Jun [nucleoplasm] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-450237] phospho-JUN [nucleoplasm] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-450237] phospho-JUN [nucleoplasm] - Bos taurus [EntityWithAccessionedSequence:R-SSC-450237] phospho-JUN [nucleoplasm] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-450237] phospho-jun [nucleoplasm] - Danio rerio [EntityWithAccessionedSequence:R-XTR-450237] phospho-jun [nucleoplasm] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-450237] phospho-JUN [nucleoplasm] - Gallus gallus [EntityWithAccessionedSequence:R-SCE-450237] phospho-GCN4 [nucleoplasm] - Saccharomyces cerevisiae
maxDepth	1
modified	[InstanceEdit:3322334] Wu, G, 2013-05-03
name	p-S63,S73-JUN p-S63,S73-c-Jun Transcription factor AP-1 (phosphorylated)
negativelyRegulates	[NegativeRegulation:9850976] Negative regulation by 'p-S63,S73-JUN [nucleoplasm]'
producedByEvent	[BlackBoxEvent:R-HSA-9851096] NPM1-ALK- and JNK-dependent JUN phosphorylation - Homo sapiens [Reaction:R-HSA-9673789] Activated JNK phosphorylates c-JUN - Homo sapiens [Reaction:R-HSA-168136] Activated JNKs phosphorylate c-JUN - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P05412] UniProt:P05412 JUN
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-450237
startCoordinate	1
updateTrackers	[UpdateTracker:9870774] Update Tracker - [EntityWithAccessionedSequence:450237] p-S63,S73-JUN [nucleoplasm] - v38:[modifyName] [UpdateTracker:9877469] Update Tracker - [EntityWithAccessionedSequence:450237] p-S63,S73-JUN [nucleoplasm] - v44:[addStartCoordinate] [UpdateTracker:9880726] Update Tracker - [EntityWithAccessionedSequence:450237] p-S63,S73-JUN [nucleoplasm] - v45:[addName]

Referrals

(updatedInstance)	[UpdateTracker:9870774] Update Tracker - [EntityWithAccessionedSequence:450237] p-S63,S73-JUN [nucleoplasm] - v38:[modifyName] [UpdateTracker:9877469] Update Tracker - [EntityWithAccessionedSequence:450237] p-S63,S73-JUN [nucleoplasm] - v44:[addStartCoordinate] [UpdateTracker:9880726] Update Tracker - [EntityWithAccessionedSequence:450237] p-S63,S73-JUN [nucleoplasm] - v45:[addName]
(output)	[BlackBoxEvent:R-HSA-9851096] NPM1-ALK- and JNK-dependent JUN phosphorylation [Reaction:R-HSA-9673789] Activated JNK phosphorylates c-JUN [Reaction:R-HSA-168136] Activated JNKs phosphorylate c-JUN
(regulator)	[NegativeRegulation:9850976] Negative regulation by 'p-S63,S73-JUN [nucleoplasm]'
(input)	[Reaction:R-HSA-168440] Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer. [Reaction:R-HSA-450292] Formation of Activated Protein 1 (AP-1) complex. cFOS/c-JUN heterodimer.
(hasComponent)	[Complex:R-HSA-450327] p-2S-cJUN:p-2S,2T-cFOS [nucleoplasm] [Complex:R-HSA-450262] p-2S-cJUN:p-2T-ATF2 [nucleoplasm]

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