Reactome | Homologues of PAK1 [cytosol]

Schema > DefinedSet > Entries

catalystActivities	[CatalystActivity:10853684] protein serine/threonine kinase activity of PAK1 [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-DME-445002] PAK1 dimer [cytosol] - Drosophila melanogaster [Complex:R-DME-445002] PAK1 dimer [cytosol] - Drosophila melanogaster [Complex:R-DME-9014578] Active PAK1:ARHGEF6 [cytosol] - Drosophila melanogaster
consumedByEvent	[Reaction:R-DME-8964619] PAK1 binds ARHGEF6 - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10849374
displayName	Homologues of PAK1 [cytosol]
hasMember	[EntityWithAccessionedSequence:R-DME-162629] PAK1 [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-DME-162629-2] PAK1 [cytosol] - Drosophila melanogaster
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-8964622] Active PAK1 [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-162629] PAK1 [cytosol] - Homo sapiens
maxDepth	2
memberOf	[CandidateSet:R-DME-442619] PAK1/3, 2 [cytosol] - Drosophila melanogaster
name	Homologues of PAK1
producedByEvent	[Reaction:R-DME-2029456] RAC1 and CDC42 activate PAK1 - Drosophila melanogaster [Reaction:R-DME-445072] Interaction of PAK1 with Rac1-GTP - Drosophila melanogaster
schemaClass	DefinedSet
species	[Species:56210] Drosophila melanogaster
stId	R-DME-162629-3

(hasMember)	[CandidateSet:R-DME-442619] PAK1/3, 2 [cytosol] [DefinedSet:R-DME-390765] PAK1,2,3 [cytosol]
(output)	[Reaction:R-DME-445072] Interaction of PAK1 with Rac1-GTP [Reaction:R-DME-2029456] RAC1 and CDC42 activate PAK1
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-8964622] Active PAK1 [cytosol] [EntityWithAccessionedSequence:R-HSA-162629] PAK1 [cytosol]
(input)	[Reaction:R-DME-8964619] PAK1 binds ARHGEF6
(hasComponent)	[Complex:R-DME-9014578] Active PAK1:ARHGEF6 [cytosol] [Complex:R-DME-2029159] RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] [Complex:R-DME-445002] PAK1 dimer [cytosol]
(physicalEntity)	[CatalystActivity:10853684] protein serine/threonine kinase activity of PAK1 [cytosol]