Reactome | Integration of provirus

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Integration of provirus Show undefined attributes

authored	[InstanceEdit:180401] Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:162591] Joshi-Tope, G, 2005-03-31 22:05:41
crossReference	[DatabaseIdentifier:12020765] Mondo:0005109
dbId	162592
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
displayName	Integration of provirus
edited	[InstanceEdit:180401] Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22
eventOf	[Pathway:R-HSA-162594] Early Phase of HIV Life Cycle - Homo sapiens
figure	[Figure:175900] /figures/integ_summary.jpg
goBiologicalProcess	[GO_BiologicalProcess:2454640] establishment of integrated proviral latency
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-8951690] Formation of RTC with integration competent viral DNA:BANF1:HMGA1:PSIP1 - Homo sapiens [Reaction:R-HSA-173115] Formation of Pre-Integration Complex (PIC) - Homo sapiens [Reaction:R-HSA-164514] Integrase binds viral DNA ends - Homo sapiens [Reaction:R-HSA-164522] Terminal (3' end) cleavage of viral DNA - Homo sapiens [Reaction:R-HSA-162590] Import of PIC to the Host Nucleus - Homo sapiens [Pathway:R-HSA-175567] Integration of viral DNA into host genomic DNA - Homo sapiens [Reaction:R-HSA-175117] 1-LTR circle formation - Homo sapiens [Pathway:R-HSA-164843] 2-LTR circle formation - Homo sapiens [Pathway:R-HSA-177539] Autointegration results in viral DNA circles - Homo sapiens
isInDisease	true
isInferred	false
lastUpdatedDate	2018-06-13
literatureReference	[LiteratureReference:177403] Retroviral DNA integration--mechanism and consequences
maxDepth	3
modified	[InstanceEdit:9847082] Weiser, Joel, 2023-10-12
name	Integration of provirus
precedingEvent	[Pathway:R-HSA-162589] Reverse Transcription of HIV RNA - Homo sapiens
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2006-11-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:188934] Bushman, FD, 2006-10-30 22:19:13
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-162592
summation	[Summation:179397] For retroviral DNA to direct production of progeny virions i...
updateTrackers	[UpdateTracker:9787831] Update Tracker - [Pathway:162592] Integration of provirus - v44:[updateContainedRLE, updateIndirectRLE] [UpdateTracker:9786283] Update Tracker - [Pathway:162592] Integration of provirus - v50:[updateContainedRLE] [UpdateTracker:9783638] Update Tracker - [Pathway:162592] Integration of provirus - v56:[updateIndirectRLE] [UpdateTracker:9779319] Update Tracker - [Pathway:162592] Integration of provirus - v65:[updateContainedRLE] [UpdateTracker:9781999] Update Tracker - [Pathway:162592] Integration of provirus - v60:[addHasEvent, updateContainedRLE] [UpdateTracker:9789234] Update Tracker - [Pathway:162592] Integration of provirus - v38:[updateContainedPathway]

Referrals

(updatedInstance)

[UpdateTracker:9787831] Update Tracker - [Pathway:162592] Integration of provirus - v44:[updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9786283] Update Tracker - [Pathway:162592] Integration of provirus - v50:[updateContainedRLE]
[UpdateTracker:9783638] Update Tracker - [Pathway:162592] Integration of provirus - v56:[updateIndirectRLE]
[UpdateTracker:9779319] Update Tracker - [Pathway:162592] Integration of provirus - v65:[updateContainedRLE]
[UpdateTracker:9781999] Update Tracker - [Pathway:162592] Integration of provirus - v60:[addHasEvent, updateContainedRLE]
[UpdateTracker:9789234] Update Tracker - [Pathway:162592] Integration of provirus - v38:[updateContainedPathway]

(hasEvent)

[Pathway:R-HSA-162594] Early Phase of HIV Life Cycle

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