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Schema
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Entries
Reverse Transcription of HIV RNA
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authored
[InstanceEdit:180401] Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22
compartment
[Compartment:70101] cytosol
created
[InstanceEdit:162591] Joshi-Tope, G, 2005-03-31 22:05:41
crossReference
[DatabaseIdentifier:12020765] Mondo:0005109
dbId
162589
disease
[Disease:1660559] Human immunodeficiency virus infectious disease
displayName
Reverse Transcription of HIV RNA
edited
[InstanceEdit:180401] Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22
eventOf
[Pathway:R-HSA-162594] Early Phase of HIV Life Cycle - Homo sapiens
figure
[Figure:182843] /figures/RT_summary.jpg
followingEvent
[Pathway:R-HSA-162592] Integration of provirus - Homo sapiens
goBiologicalProcess
[GO_BiologicalProcess:17126] RNA-templated DNA biosynthetic process
hasDiagram
false
hasEHLD
false
hasEvent
[Pathway:R-HSA-164516] Minus-strand DNA synthesis - Homo sapiens
[Pathway:R-HSA-164525] Plus-strand DNA synthesis - Homo sapiens
isInDisease
true
isInferred
false
lastUpdatedDate
2020-09-24
literatureReference
[LiteratureReference:182861] Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor.
[LiteratureReference:182858] Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA.
[LiteratureReference:175795] RNA-dependent DNA polymerase in virions of RNA tumour viruses
[LiteratureReference:175683] RNA-dependent DNA polymerase in virions of Rous sarcoma virus
[Book:175762] 9780879695712 Reverse Transcriptase and the Generation of Retroviral DNA Retroviruses Coffin, JM
[LiteratureReference:182875] Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimer
[LiteratureReference:175646] The HIV-1 reverse transcription (RT) process as target for RT inhibitors
[LiteratureReference:182845] What is the orientation of DNA polymerases on their templates?
maxDepth
3
modified
[InstanceEdit:9847082] Weiser, Joel, 2023-10-12
name
Reverse Transcription of HIV RNA
precedingEvent
[Reaction:R-HSA-164527] Annealing of 3'-end of unwound transfer RNA primer with genomic RNA - Homo sapiens
relatedSpecies
[Species:164493] Human immunodeficiency virus 1
releaseDate
2006-11-14
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:188936] Hughes, SH, 2006-10-30 22:00:51
schemaClass
Pathway
species
[Species:48887] Homo sapiens
stId
R-HSA-162589
summation
[Summation:175917] The RNA genome of HIV-1, like that of other retroviruses, is...
updateTrackers
[UpdateTracker:9776663] Update Tracker - [Pathway:162589] Reverse Transcription of HIV RNA - v74:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9791882] Update Tracker - [Pathway:162589] Reverse Transcription of HIV RNA - v25:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9783124] Update Tracker - [Pathway:162589] Reverse Transcription of HIV RNA - v57:[updateIndirectRLE]
[UpdateTracker:9789265] Update Tracker - [Pathway:162589] Reverse Transcription of HIV RNA - v38:[addLiteratureReference]
Referrals
(updatedInstance)
[UpdateTracker:9776663] Update Tracker - [Pathway:162589] Reverse Transcription of HIV RNA - v74:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9791882] Update Tracker - [Pathway:162589] Reverse Transcription of HIV RNA - v25:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9783124] Update Tracker - [Pathway:162589] Reverse Transcription of HIV RNA - v57:[updateIndirectRLE]
[UpdateTracker:9789265] Update Tracker - [Pathway:162589] Reverse Transcription of HIV RNA - v38:[addLiteratureReference]
(hasEvent)
[Pathway:R-HSA-162594] Early Phase of HIV Life Cycle
(precedingEvent)
[Pathway:R-HSA-162592] Integration of provirus
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