Reactome | YAP1 [nucleoplasm]

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YAP1 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-2064401] YAP1:TJP2 [nucleoplasm] - Homo sapiens [Complex:R-HSA-8956638] RUNX1:CBFB:YAP1 [nucleoplasm] - Homo sapiens [Complex:R-HSA-9909630] YAP1:WWNT1:TEADs:CD274 gene [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-8956659] ABL1 phosphorylates YAP1 - Homo sapiens [Reaction:R-HSA-8956639] RUNX1 binds YAP1 - Homo sapiens [Reaction:R-HSA-8871266] YAP1 binds TEAD3 - Homo sapiens [Reaction:R-HSA-8871260] YAP1 binds TEAD2 - Homo sapiens [Reaction:R-HSA-2032775] YAP1 binds TEAD1 - Homo sapiens [Reaction:R-HSA-8871265] YAP1 binds TEAD4 - Homo sapiens [Reaction:R-HSA-9909654] YAP1/TAZ binding to CD274 gene - Homo sapiens
created	[InstanceEdit:1253306] Orlic-Milacic, Marija, 2011-04-27
dbId	1253322
displayName	YAP1 [nucleoplasm]
endCoordinate	504
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-1253322] Yap1 [nucleoplasm] - Mus musculus [EntityWithAccessionedSequence:R-RNO-1253322] Yap1 [nucleoplasm] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-1253322] YAP1 [nucleoplasm] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-1253322] YAP1 [nucleoplasm] - Bos taurus [EntityWithAccessionedSequence:R-SSC-1253322] YAP1 [nucleoplasm] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-1253322] yap1 [nucleoplasm] - Danio rerio [EntityWithAccessionedSequence:R-XTR-1253322] yap1 [nucleoplasm] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-1253322] YAP1 [nucleoplasm] - Gallus gallus [EntityWithAccessionedSequence:R-DME-1253322] yki [nucleoplasm] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-1253322] yap-1 [nucleoplasm] - Caenorhabditis elegans
markingReferences	[MarkerReference:9839464] YAP1 [nucleoplasm] Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin [MarkerReference:9937176] YAP1 [nucleoplasm] Mechanosignalling via integrins directs fate decisions of pancreatic progenitors
maxDepth	1
name	YAP1
producedByEvent	[Reaction:R-HSA-2032770] Translocation of YAP1 to the nucleus - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P46937] UniProt:P46937 YAP1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-1253322
startCoordinate	1

Referrals

(proteinMarker)	[Cell:R-HSA-9725559] keratinocyte stem cell of skin epidermis basal layer [Cell:R-HSA-9910609] pancreatic trunk bipotent progenitor cell
(marker)	[MarkerReference:9839464] YAP1 [nucleoplasm] Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin [MarkerReference:9937176] YAP1 [nucleoplasm] Mechanosignalling via integrins directs fate decisions of pancreatic progenitors
(input)	[Reaction:R-HSA-8956659] ABL1 phosphorylates YAP1 [Reaction:R-HSA-8956639] RUNX1 binds YAP1 [Reaction:R-HSA-9909654] YAP1/TAZ binding to CD274 gene [Reaction:R-HSA-8871266] YAP1 binds TEAD3 [Reaction:R-HSA-8871260] YAP1 binds TEAD2 [Reaction:R-HSA-2032775] YAP1 binds TEAD1 [Reaction:R-HSA-8871265] YAP1 binds TEAD4
(hasComponent)	[Complex:R-HSA-8956638] RUNX1:CBFB:YAP1 [nucleoplasm] [Complex:R-HSA-9909630] YAP1:WWNT1:TEADs:CD274 gene [nucleoplasm] [Complex:R-HSA-8951678] YAP1:TEAD1,TEAD4,(TEAD2,TEAD3) [nucleoplasm] [Complex:R-HSA-8869638] TEAD3:YAP1 [nucleoplasm] [Complex:R-HSA-8869640] TEAD2:YAP1 [nucleoplasm] [Complex:R-HSA-8869643] TEAD1:YAP1 [nucleoplasm] [Complex:R-HSA-8869641] TEAD4:YAP1 [nucleoplasm] [Complex:R-HSA-2064401] YAP1:TJP2 [nucleoplasm] [Complex:R-HSA-1253347] ERBB4s80:YAP1 [nucleoplasm]
(activeUnit)	[PositiveGeneExpressionRegulation:9618565] Positive gene expression regulation by 'PMP22 gene:EGR2:SOX10:TEAD1:WWTR1,YAP1 [nucleoplasm]'
(output)	[Reaction:R-HSA-2032770] Translocation of YAP1 to the nucleus

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