Reactome | YAP1 binds TEAD1

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YAP1 binds TEAD1 Show undefined attributes

authored	[InstanceEdit:2085531] D'Eustachio, P, 2012-02-03
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:2032766] D'Eustachio, P, 2012-01-06
dbId	2032775
displayName	YAP1 binds TEAD1
edited	[InstanceEdit:2032771] D'Eustachio, P, 2012-01-06
eventOf	[Pathway:R-HSA-2032785] YAP1- and WWTR1 (TAZ)-stimulated gene expression - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-1989766] Expression of CTGF - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-2032774] TEAD1 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-1253322] YAP1 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2032765] TEADs mediate nuclear retention of TAZ to promote oncogenic transformation
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	YAP1 binds TEAD1
orthologousEvent	[Reaction:R-CFA-2032775] YAP1 binds TEAD1 - Canis familiaris [Reaction:R-CEL-2032775] YAP1 binds TEAD1 - Caenorhabditis elegans [Reaction:R-DME-2032775] YAP1 binds TEAD1 - Drosophila melanogaster [Reaction:R-GGA-2032775] YAP1 binds TEAD1 - Gallus gallus [Reaction:R-DRE-2032775] YAP1 binds TEAD1 - Danio rerio [Reaction:R-SSC-2032775] YAP1 binds TEAD1 - Sus scrofa [Reaction:R-BTA-2032775] YAP1 binds TEAD1 - Bos taurus [Reaction:R-RNO-2032775] YAP1 binds TEAD1 - Rattus norvegicus [Reaction:R-MMU-2032775] YAP1 binds TEAD1 - Mus musculus
output	[Complex:R-HSA-8869643] TEAD1:YAP1 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-2032770] Translocation of YAP1 to the nucleus - Homo sapiens
releaseDate	2012-03-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2085532] Sudol, M, 2012-02-03
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2032775
summation	[Summation:2032778] In the nucleus the YAP1 transcriptional coactivator can bind...
updateTrackers	[UpdateTracker:9783260] Update Tracker - [Reaction:2032775] YAP1 binds TEAD1 - v57:[add_removeInput, add_removeOutput]

Referrals

(updatedInstance)	[UpdateTracker:9783260] Update Tracker - [Reaction:2032775] YAP1 binds TEAD1 - v57:[add_removeInput, add_removeOutput]
(precedingEvent)	[BlackBoxEvent:R-HSA-1989766] Expression of CTGF
(hasEvent)	[Pathway:R-HSA-2032785] YAP1- and WWTR1 (TAZ)-stimulated gene expression