Reactome | ABL1 phosphorylates YAP1

Schema > Reaction > Entries

ABL1 phosphorylates YAP1 Show undefined attributes

authored	[InstanceEdit:8938982] Orlic-Milacic, Marija, 2016-09-14
catalystActivity	[CatalystActivity:5686585] protein tyrosine kinase activity of p-S456-ABL1 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8956660] Orlic-Milacic, Marija, 2017-01-23
dbId	8956659
displayName	ABL1 phosphorylates YAP1
edited	[InstanceEdit:9005626] Orlic-Milacic, Marija, 2017-05-09
eventOf	[Pathway:R-HSA-8939236] RUNX1 regulates transcription of genes involved in differentiation of HSCs - Homo sapiens
followingEvent	[Reaction:R-HSA-8956676] YAP1 binds TP73 - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-1253322] YAP1 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8956641] Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage
modified	[InstanceEdit:10740525] Wright, Adam, 2024-03-08
name	ABL1 phosphorylates YAP1
orthologousEvent	[Reaction:R-MMU-8956659] ABL1 phosphorylates YAP1 - Mus musculus [Reaction:R-CEL-8956659] ABL1 phosphorylates YAP1 - Caenorhabditis elegans [Reaction:R-GGA-8956659] ABL1 phosphorylates YAP1 - Gallus gallus [Reaction:R-XTR-8956659] ABL1 phosphorylates YAP1 - Xenopus tropicalis [Reaction:R-SSC-8956659] ABL1 phosphorylates YAP1 - Sus scrofa [Reaction:R-BTA-8956659] ABL1 phosphorylates YAP1 - Bos taurus [Reaction:R-CFA-8956659] ABL1 phosphorylates YAP1 - Canis familiaris [Reaction:R-RNO-8956659] ABL1 phosphorylates YAP1 - Rattus norvegicus
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-8956661] p-Y407-YAP1 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-5686578] Activated ATM phosphorylates ABL1 - Homo sapiens
releaseDate	2017-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9005627] Ito, Yoshiaki, 2016-12-20 [InstanceEdit:9005628] Chuang, Linda Shyue Huey, 2016-12-20
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8956659
summation	[Summation:8956667] In response to DNA damage, ABL1 phosphorylates YAP1 on tyros...

Referrals

(hasEvent)	[Pathway:R-HSA-8939236] RUNX1 regulates transcription of genes involved in differentiation of HSCs
(precedingEvent)	[Reaction:R-HSA-8956676] YAP1 binds TP73