Reactome | YAP1 binds TEAD4

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YAP1 binds TEAD4 Show undefined attributes

authored	[InstanceEdit:2085531] D'Eustachio, P, 2012-02-03
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8871261] Jupe, Steve, 2016-05-13
dbId	8871265
displayName	YAP1 binds TEAD4
edited	[InstanceEdit:2032771] D'Eustachio, P, 2012-01-06
eventOf	[Pathway:R-HSA-2032785] YAP1- and WWTR1 (TAZ)-stimulated gene expression - Homo sapiens
followingEvent	[Reaction:R-HSA-9796225] TEAD2,TEAD4:YAP1, TBXT, FOXH1, and SMAD2,3 bind the FOXA2 gene - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-2032780] TEAD4 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-1253322] YAP1 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2032765] TEADs mediate nuclear retention of TAZ to promote oncogenic transformation
modified	[InstanceEdit:10740525] Wright, Adam, 2024-03-08
name	YAP1 binds TEAD4
orthologousEvent	[Reaction:R-CEL-8871265] YAP1 binds TEAD4 - Caenorhabditis elegans [Reaction:R-GGA-8871265] YAP1 binds TEAD4 - Gallus gallus [Reaction:R-SSC-8871265] YAP1 binds TEAD4 - Sus scrofa [Reaction:R-BTA-8871265] YAP1 binds TEAD4 - Bos taurus [Reaction:R-CFA-8871265] YAP1 binds TEAD4 - Canis familiaris [Reaction:R-RNO-8871265] YAP1 binds TEAD4 - Rattus norvegicus [Reaction:R-MMU-8871265] YAP1 binds TEAD4 - Mus musculus
output	[Complex:R-HSA-8869641] TEAD4:YAP1 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-2032770] Translocation of YAP1 to the nucleus - Homo sapiens
releaseDate	2012-03-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2085532] Sudol, M, 2012-02-03
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8871265
summation	[Summation:8871264] The YAP1 transcriptional coactivator can bind any one of the...

Referrals

(precedingEvent)	[Reaction:R-HSA-9796225] TEAD2,TEAD4:YAP1, TBXT, FOXH1, and SMAD2,3 bind the FOXA2 gene
(hasEvent)	[Pathway:R-HSA-2032785] YAP1- and WWTR1 (TAZ)-stimulated gene expression