Reactome | Apoptotic factor-mediated response

Schema > Pathway > Entries

Apoptotic factor-mediated response Show undefined attributes

authored	[InstanceEdit:9013808] Shamovsky, Veronica, 2017-07-26
created	[InstanceEdit:111451] Alnemri, E, 2004-02-17 00:23:30
crossReference	[DatabaseIdentifier:12819577] BioModels Database:BIOMD0000000256 [DatabaseIdentifier:12819457] BioModels Database:BIOMD0000000220
dbId	111471
displayName	Apoptotic factor-mediated response
edited	[InstanceEdit:9627669] Shamovsky, Veronica, 2018-11-02
eventOf	[Pathway:R-HSA-109606] Intrinsic Pathway for Apoptosis - Homo sapiens
figure	[Figure:114484] /figures/apoptotic_factor_responses.jpg
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-HSA-111457] Release of apoptotic factors from the mitochondria - Homo sapiens [Pathway:R-HSA-111461] Cytochrome c-mediated apoptotic response - Homo sapiens [Pathway:R-HSA-111469] SMAC, XIAP-regulated apoptotic response - Homo sapiens [Reaction:R-HSA-9645694] p14ARF binds C1QBP - Homo sapiens [BlackBoxEvent:R-HSA-9645692] C1QBP promotes translocation of p14ARF to the mitochondrial matrix - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2021-03-24
literatureReference	[LiteratureReference:140365] Toxic proteins released from mitochondria in cell death [LiteratureReference:140369] IAP proteins: blocking the road to death's door
maxDepth	5
modified	[InstanceEdit:12819426] Weiser, Joel, 2026-02-23
name	Apoptotic factor-mediated response
orthologousEvent	[Pathway:R-PFA-111471] Apoptotic factor-mediated response - Plasmodium falciparum [Pathway:R-SCE-111471] Apoptotic factor-mediated response - Saccharomyces cerevisiae [Pathway:R-SPO-111471] Apoptotic factor-mediated response - Schizosaccharomyces pombe [Pathway:R-DDI-111471] Apoptotic factor-mediated response - Dictyostelium discoideum [Pathway:R-CEL-111471] Apoptotic factor-mediated response - Caenorhabditis elegans [Pathway:R-DME-111471] Apoptotic factor-mediated response - Drosophila melanogaster [Pathway:R-GGA-111471] Apoptotic factor-mediated response - Gallus gallus [Pathway:R-XTR-111471] Apoptotic factor-mediated response - Xenopus tropicalis [Pathway:R-DRE-111471] Apoptotic factor-mediated response - Danio rerio [Pathway:R-SSC-111471] Apoptotic factor-mediated response - Sus scrofa [Pathway:R-BTA-111471] Apoptotic factor-mediated response - Bos taurus [Pathway:R-CFA-111471] Apoptotic factor-mediated response - Canis familiaris [Pathway:R-RNO-111471] Apoptotic factor-mediated response - Rattus norvegicus [Pathway:R-MMU-111471] Apoptotic factor-mediated response - Mus musculus
releaseDate	2018-12-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9627969] Matthews, Lisa, 2018-11-05
revised	[InstanceEdit:9627661] Shamovsky, Veronica, 2018-11-02
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-111471
summation	[Summation:212955] In response to apoptotic signals, mitochondrial proteins are...
updateTrackers	[UpdateTracker:9789837] Update Tracker - [Pathway:111471] Apoptotic factor-mediated response - v37:[updateContainedPathway] [UpdateTracker:9778911] Update Tracker - [Pathway:111471] Apoptotic factor-mediated response - v67:[addHasEvent, modifyText, updateContainedPathway, updateIndirectRLE] [UpdateTracker:9777581] Update Tracker - [Pathway:111471] Apoptotic factor-mediated response - v70:[addHasEvent] [UpdateTracker:9776294] Update Tracker - [Pathway:111471] Apoptotic factor-mediated response - v76:[updateIndirectRLE] [UpdateTracker:9786480] Update Tracker - [Pathway:111471] Apoptotic factor-mediated response - v49:[updateContainedPathway] [UpdateTracker:9789176] Update Tracker - [Pathway:111471] Apoptotic factor-mediated response - v38:[updateContainedPathway] [UpdateTracker:9791948] Update Tracker - [Pathway:111471] Apoptotic factor-mediated response - v24:[addSummation, updateContainedPathway]

Referrals

(updatedInstance)

(hasEvent)

[Pathway:R-HSA-109606] Intrinsic Pathway for Apoptosis

Cite Us!