In response to apoptotic signals, mitochondrial proteins are...
| created | [InstanceEdit:212957] Matthews, L, 2008-02-15 23:38:23 |
| dbId | 212955 |
| displayName | In response to apoptotic signals, mitochondrial proteins are... |
| literatureReference | |
| modified | [InstanceEdit:9627088] Shamovsky, Veronica, 2018-11-01 |
| schemaClass | Summation |
| text | In response to apoptotic signals, mitochondrial proteins are released into the cytosol and activate both caspase-dependent and -independent cell death pathways. Cytochrome c induces apoptosome formation, AIF and endonuclease G function in caspase independent apoptotic nuclear DNA damage. Smac/DIABLO and HtrA2/OMI promote both caspase activation and caspase-independent cytotoxicity (Saelens et al., 2004). |
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