Reactome | Apoptotic factor-mediated response

Schema > Pathway > Entries

created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10329097
displayName	Apoptotic factor-mediated response
eventOf	[Pathway:R-CFA-109606] Intrinsic Pathway for Apoptosis - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-CFA-111457] Release of apoptotic factors from the mitochondria - Canis familiaris [Pathway:R-CFA-111461] Cytochrome c-mediated apoptotic response - Canis familiaris [Pathway:R-CFA-111469] SMAC, XIAP-regulated apoptotic response - Canis familiaris
inferredFrom	[Pathway:R-HSA-111471] Apoptotic factor-mediated response - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	5
name	Apoptotic factor-mediated response
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49646] Canis familiaris
stId	R-CFA-111471
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-109606] Intrinsic Pathway for Apoptosis
(inferredTo)	[Pathway:R-HSA-111471] Apoptotic factor-mediated response

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