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Entries
Cytochrome c-mediated apoptotic response
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authored
[InstanceEdit:139820] Matthews, L, 2004-08-06 15:00:00
compartment
[Compartment:70101] cytosol
created
[InstanceEdit:111451] Alnemri, E, 2004-02-17 00:23:30
dbId
111461
displayName
Cytochrome c-mediated apoptotic response
eventOf
[Pathway:R-HSA-111471] Apoptotic factor-mediated response - Homo sapiens
figure
[Figure:114493] /figures/cytoC_mediated_response.jpg
hasDiagram
false
hasEHLD
false
hasEvent
[Pathway:R-HSA-111458] Formation of apoptosome - Homo sapiens
[Pathway:R-HSA-111459] Activation of caspases through apoptosome-mediated cleavage - Homo sapiens
isInDisease
false
isInferred
false
lastUpdatedDate
2018-12-13
literatureReference
[LiteratureReference:141212] Apo cytochrome c inhibits caspases by preventing apoptosome formation
maxDepth
4
modified
[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
name
Cytochrome c-mediated apoptotic response
orthologousEvent
[Pathway:R-DME-111461] Cytochrome c-mediated apoptotic response - Drosophila melanogaster
[Pathway:R-GGA-111461] Cytochrome c-mediated apoptotic response - Gallus gallus
[Pathway:R-XTR-111461] Cytochrome c-mediated apoptotic response - Xenopus tropicalis
[Pathway:R-DRE-111461] Cytochrome c-mediated apoptotic response - Danio rerio
[Pathway:R-SSC-111461] Cytochrome c-mediated apoptotic response - Sus scrofa
[Pathway:R-BTA-111461] Cytochrome c-mediated apoptotic response - Bos taurus
[Pathway:R-CFA-111461] Cytochrome c-mediated apoptotic response - Canis familiaris
[Pathway:R-RNO-111461] Cytochrome c-mediated apoptotic response - Rattus norvegicus
[Pathway:R-MMU-111461] Cytochrome c-mediated apoptotic response - Mus musculus
precedingEvent
[Reaction:R-HSA-114284] Release of Cytochrome c from mitochondria - Homo sapiens
releaseDate
2004-10-27
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:165094] Vaux, D, 0000-00-00 00:00:00
[InstanceEdit:9620504] Matthews, Lisa, 2018-09-25
revised
[InstanceEdit:9628285] Shamovsky, Veronica, 2018-11-07
schemaClass
Pathway
species
[Species:48887] Homo sapiens
stId
R-HSA-111461
summation
[Summation:140362] Upon its release from the mitochondrial intermembrane space,...
updateTrackers
[UpdateTracker:9787843] Update Tracker - [Pathway:111461] Cytochrome c-mediated apoptotic response - v44:[updateIndirectRLE]
[UpdateTracker:9791943] Update Tracker - [Pathway:111461] Cytochrome c-mediated apoptotic response - v24:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9783892] Update Tracker - [Pathway:111461] Cytochrome c-mediated apoptotic response - v55:[updateIndirectRLE]
[UpdateTracker:9792121] Update Tracker - [Pathway:111461] Cytochrome c-mediated apoptotic response - v23:[updateIndirectRLE]
[UpdateTracker:9791804] Update Tracker - [Pathway:111461] Cytochrome c-mediated apoptotic response - v25:[updateIndirectRLE]
[UpdateTracker:9778824] Update Tracker - [Pathway:111461] Cytochrome c-mediated apoptotic response - v67:[modifyText, updateContainedPathway, updateIndirectRLE]
Referrals
(updatedInstance)
[UpdateTracker:9787843] Update Tracker - [Pathway:111461] Cytochrome c-mediated apoptotic response - v44:[updateIndirectRLE]
[UpdateTracker:9791943] Update Tracker - [Pathway:111461] Cytochrome c-mediated apoptotic response - v24:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9783892] Update Tracker - [Pathway:111461] Cytochrome c-mediated apoptotic response - v55:[updateIndirectRLE]
[UpdateTracker:9792121] Update Tracker - [Pathway:111461] Cytochrome c-mediated apoptotic response - v23:[updateIndirectRLE]
[UpdateTracker:9791804] Update Tracker - [Pathway:111461] Cytochrome c-mediated apoptotic response - v25:[updateIndirectRLE]
[UpdateTracker:9778824] Update Tracker - [Pathway:111461] Cytochrome c-mediated apoptotic response - v67:[modifyText, updateContainedPathway, updateIndirectRLE]
(hasEvent)
[Pathway:R-HSA-111471] Apoptotic factor-mediated response
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