Reactome | GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol]

Schema > Complex > Entries

GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] Show undefined attributes

catalystActivities	[CatalystActivity:109816] guanyl-nucleotide exchange factor activity of GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol]
compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-HSA-109823] MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 - Homo sapiens
created	[InstanceEdit:109781] Schmidt, EE, 2004-01-21 04:32:59
dbId	109800
displayName	GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol]
hasComponent	[Complex:R-HSA-109797] GRB2-1:SOS1 [cytosol] [DefinedSet:R-HSA-112322] p-Y-IRS1,p-Y-IRS2 [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-109800] GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] - Mus musculus [Complex:R-RNO-109800] GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] - Rattus norvegicus [Complex:R-CFA-109800] GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] - Canis familiaris [Complex:R-BTA-109800] GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] - Bos taurus [Complex:R-SSC-109800] GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] - Sus scrofa [Complex:R-DRE-109800] GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] - Danio rerio [Complex:R-XTR-109800] GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] - Xenopus tropicalis [Complex:R-GGA-109800] GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] - Gallus gallus [Complex:R-DME-109800] GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] - Drosophila melanogaster
maxDepth	3
memberOf	[DefinedSet:R-HSA-5672601] RAS GEFs [plasma membrane] - Homo sapiens
modified	[InstanceEdit:5686058] Jupe, Steve, 2015-03-31
name	GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2
producedByEvent	[Reaction:R-HSA-74736] GRB2-1:SOS1 binds p-IRS1,p-IRS2 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-109800
updateTrackers	[UpdateTracker:9898300] Update Tracker - [Complex:109800] GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] - v63:[updateContainedComponent] [UpdateTracker:9892523] Update Tracker - [Complex:109800] GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] - v53:[modifyName, updateContainedComponent] [UpdateTracker:9869041] Update Tracker - [Complex:109800] GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] - v32:[updateContainedComponent] [UpdateTracker:9870543] Update Tracker - [Complex:109800] GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] - v38:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9898300] Update Tracker - [Complex:109800] GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] - v63:[updateContainedComponent] [UpdateTracker:9892523] Update Tracker - [Complex:109800] GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] - v53:[modifyName, updateContainedComponent] [UpdateTracker:9869041] Update Tracker - [Complex:109800] GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] - v32:[updateContainedComponent] [UpdateTracker:9870543] Update Tracker - [Complex:109800] GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] - v38:[updateContainedComponent]
(physicalEntity)	[CatalystActivity:109816] guanyl-nucleotide exchange factor activity of GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol]
(input)	[Reaction:R-HSA-109823] MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2
(output)	[Reaction:R-HSA-74736] GRB2-1:SOS1 binds p-IRS1,p-IRS2
(hasMember)	[DefinedSet:R-HSA-5672601] RAS GEFs [plasma membrane]

© 2026 Reactome

Cite Us!