Reactome | IGF1,2 [extracellular region]

Schema > DefinedSet > Entries

IGF1,2 [extracellular region] Show undefined attributes

compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-DRE-381423] IGF:IGFBP5:ALS [extracellular region] - Danio rerio [Complex:R-DRE-381536] IGF:IGFBP3:ALS [extracellular region] - Danio rerio
consumedByEvent	[Reaction:R-DRE-381545] Formation of the IGF:IGFBP5:ALS complex - Danio rerio [Reaction:R-DRE-381503] IGFBP6 binds IGF forming IGF:IGFBP6 - Danio rerio [Reaction:R-DRE-381487] IGFBP1 binds IGF forming IGF:IGFBP1 - Danio rerio [Reaction:R-DRE-381412] IGFBP2 binds IGF forming IGF:IGFBP2 - Danio rerio [Reaction:R-DRE-381496] Formation of the IGF:IGFBP3:ALS complex - Danio rerio
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10581827
displayName	IGF1,2 [extracellular region]
hasMember	[EntityWithAccessionedSequence:R-DRE-2404178] igf1 [extracellular region] - Danio rerio [EntityWithAccessionedSequence:R-DRE-2404175] igf2b [extracellular region] - Danio rerio
inDisease	false
inferredFrom	[DefinedSet:R-HSA-381451] IGF1,2 [extracellular region] - Homo sapiens
maxDepth	2
memberOf	[DefinedSet:R-DRE-481033] Platelet alpha granule contents [extracellular region] - Danio rerio
name	IGF1,2 Insulin-like Growth Factor
producedByEvent	[Reaction:R-DRE-381500] Cathepsin G proteolyzes IGF:IGFBP3:ALS - Danio rerio [Reaction:R-DRE-381537] PAPP-A2 proteolyzes IGF:IGFBP5:ALS - Danio rerio [Reaction:R-DRE-381446] Thrombin proteolyzes IGF:IGFBP3:ALS - Danio rerio [Reaction:R-DRE-381435] Matrix metalloproteinase proteolyzes IGF:IGFBP3:ALS - Danio rerio [Reaction:R-DRE-381461] Plasmin proteolyzes IGF:IGFBP-3:ALS - Danio rerio
schemaClass	DefinedSet
species	[Species:68323] Danio rerio
stId	R-DRE-381451

Referrals

(output)	[Reaction:R-DRE-381435] Matrix metalloproteinase proteolyzes IGF:IGFBP3:ALS [Reaction:R-DRE-381500] Cathepsin G proteolyzes IGF:IGFBP3:ALS [Reaction:R-DRE-381461] Plasmin proteolyzes IGF:IGFBP-3:ALS [Reaction:R-DRE-381537] PAPP-A2 proteolyzes IGF:IGFBP5:ALS [Reaction:R-DRE-381446] Thrombin proteolyzes IGF:IGFBP3:ALS
(input)	[Reaction:R-DRE-381545] Formation of the IGF:IGFBP5:ALS complex [Reaction:R-DRE-381496] Formation of the IGF:IGFBP3:ALS complex [Reaction:R-DRE-381503] IGFBP6 binds IGF forming IGF:IGFBP6 [Reaction:R-DRE-381412] IGFBP2 binds IGF forming IGF:IGFBP2 [Reaction:R-DRE-381487] IGFBP1 binds IGF forming IGF:IGFBP1
(hasComponent)	[Complex:R-DRE-381423] IGF:IGFBP5:ALS [extracellular region] [Complex:R-DRE-381536] IGF:IGFBP3:ALS [extracellular region] [Complex:R-DRE-381482] IGF:IGFBP6 [extracellular region] [Complex:R-DRE-381473] IGF:IGFBP2 [extracellular region] [Complex:R-DRE-381539] IGF:IGFBP1 [extracellular region]
(hasMember)	[DefinedSet:R-DRE-481033] Platelet alpha granule contents [extracellular region]
(inferredTo)	[DefinedSet:R-HSA-381451] IGF1,2 [extracellular region]

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