Reactome | DAGs [plasma membrane]

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DAGs [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-DDI-5607700] DAGs:p-T507,S645,S664-PRKCD [plasma membrane] - Dictyostelium discoideum [Complex:R-CFA-5218773] DAG:active PKC:Ca+2 [plasma membrane] - Canis familiaris [Complex:R-MMU-2685677] RasGRP1:DAG:Ca2+ [plasma membrane] - Mus musculus
consumedByEvent	[Reaction:R-SCE-5607734] PKC-delta translocates to plasma membrane - Saccharomyces cerevisiae [Reaction:R-SPO-5607734] PKC-delta translocates to plasma membrane - Schizosaccharomyces pombe [Reaction:R-DDI-5607734] PKC-delta translocates to plasma membrane - Dictyostelium discoideum [Reaction:R-CEL-5607734] PKC-delta translocates to plasma membrane - Caenorhabditis elegans [Reaction:R-DME-5607734] PKC-delta translocates to plasma membrane - Drosophila melanogaster [Reaction:R-GGA-5607734] PKC-delta translocates to plasma membrane - Gallus gallus [Reaction:R-XTR-5607734] PKC-delta translocates to plasma membrane - Xenopus tropicalis [Reaction:R-DRE-5607734] PKC-delta translocates to plasma membrane - Danio rerio [Reaction:R-SSC-5607734] PKC-delta translocates to plasma membrane - Sus scrofa [Reaction:R-BTA-5607734] PKC-delta translocates to plasma membrane - Bos taurus [Reaction:R-CFA-5607734] PKC-delta translocates to plasma membrane - Canis familiaris [Reaction:R-RNO-5607734] PKC-delta translocates to plasma membrane - Rattus norvegicus [Reaction:R-MMU-5607734] PKC-delta translocates to plasma membrane - Mus musculus [Reaction:R-HSA-5607734] PKC-delta translocates to plasma membrane - Homo sapiens [BlackBoxEvent:R-MMU-1169494] Rasgrp1 and Rasgrp3 are recruited to the membrane and phosphorylated - Mus musculus [Reaction:R-MMU-2730865] RasGRP interacts with DAG and Ca2+ - Mus musculus [Reaction:R-HSA-2730871] RasGRP interacts with DAG and Ca2+ - Homo sapiens [Reaction:R-SCE-5218813] DAG and Ca+2 bind to PKC and tether it to membrane - Saccharomyces cerevisiae [Reaction:R-SPO-5218813] DAG and Ca+2 bind to PKC and tether it to membrane - Schizosaccharomyces pombe [Reaction:R-DDI-5218813] DAG and Ca+2 bind to PKC and tether it to membrane - Dictyostelium discoideum [Reaction:R-CEL-5218813] DAG and Ca+2 bind to PKC and tether it to membrane - Caenorhabditis elegans [Reaction:R-DME-5218813] DAG and Ca+2 bind to PKC and tether it to membrane - Drosophila melanogaster [Reaction:R-GGA-5218813] DAG and Ca+2 bind to PKC and tether it to membrane - Gallus gallus [Reaction:R-XTR-5218813] DAG and Ca+2 bind to PKC and tether it to membrane - Xenopus tropicalis [Reaction:R-DRE-5218813] DAG and Ca+2 bind to PKC and tether it to membrane - Danio rerio [Reaction:R-SSC-5218813] DAG and Ca+2 bind to PKC and tether it to membrane - Sus scrofa [Reaction:R-BTA-5218813] DAG and Ca+2 bind to PKC and tether it to membrane - Bos taurus [Reaction:R-CFA-5218813] DAG and Ca+2 bind to PKC and tether it to membrane - Canis familiaris [Reaction:R-RNO-5218813] DAG and Ca+2 bind to PKC and tether it to membrane - Rattus norvegicus [Reaction:R-MMU-5218813] DAG and Ca+2 bind to PKC and tether it to membrane - Mus musculus [Reaction:R-HSA-5218813] DAG and Ca+2 bind to PKC and tether it to membrane - Homo sapiens [Reaction:R-SCE-202328] Translocation of PKC theta to plasma membrane - Saccharomyces cerevisiae [Reaction:R-SPO-202328] Translocation of PKC theta to plasma membrane - Schizosaccharomyces pombe [Reaction:R-DDI-202328] Translocation of PKC theta to plasma membrane - Dictyostelium discoideum [Reaction:R-CEL-202328] Translocation of PKC theta to plasma membrane - Caenorhabditis elegans [Reaction:R-DME-202328] Translocation of PKC theta to plasma membrane - Drosophila melanogaster [Reaction:R-GGA-202328] Translocation of PKC theta to plasma membrane - Gallus gallus [Reaction:R-SSC-202328] Translocation of PKC theta to plasma membrane - Sus scrofa [Reaction:R-BTA-202328] Translocation of PKC theta to plasma membrane - Bos taurus [Reaction:R-CFA-202328] Translocation of PKC theta to plasma membrane - Canis familiaris [Reaction:R-RNO-202328] Translocation of PKC theta to plasma membrane - Rattus norvegicus [Reaction:R-MMU-202328] Translocation of PKC theta to plasma membrane - Mus musculus [Reaction:R-HSA-202328] Translocation of PKC theta to plasma membrane - Homo sapiens
created	[InstanceEdit:112274] Schmidt, EE, 2004-04-19 12:06:05
crossReference	[DatabaseIdentifier:29669] COMPOUND:C00165
dbId	112275
displayName	DAGs [plasma membrane]
inDisease	false
maxDepth	1
modified	[InstanceEdit:9619952] Wu, G, 2018-09-19
name	DAGs diacylglycerols diglyceride DAG
positivelyRegulates	[PositiveRegulation:R-XLA-8855329] Positive regulation by 'DAGs [plasma membrane]' [PositiveRegulation:R-HSA-8855331] Positive regulation by 'DAGs [plasma membrane]'
producedByEvent	[Reaction:R-MMU-9032476] Epor-associated Plcg hydrolyzes 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate - Mus musculus [Reaction:R-HSA-9032478] EPOR-associated PLCG hydrolyzes 1-Phosphatidyl-1D-myo-inositol 4,5-bisphosphate - Homo sapiens [Reaction:R-HSA-9680388] CSF1R-associated PLCG2 hydrolyzes phosphatidylcholine - Homo sapiens [Reaction:R-PFA-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 - Plasmodium falciparum [Reaction:R-SCE-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 - Saccharomyces cerevisiae [Reaction:R-SPO-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 - Schizosaccharomyces pombe [Reaction:R-DDI-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 - Dictyostelium discoideum [Reaction:R-CEL-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 - Caenorhabditis elegans [Reaction:R-DME-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 - Drosophila melanogaster [Reaction:R-GGA-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 - Gallus gallus [Reaction:R-XTR-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 - Xenopus tropicalis [Reaction:R-SSC-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 - Sus scrofa [Reaction:R-BTA-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 - Bos taurus [Reaction:R-CFA-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 - Canis familiaris [Reaction:R-RNO-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 - Rattus norvegicus [Reaction:R-MMU-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 - Mus musculus [Reaction:R-HSA-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 - Homo sapiens [Reaction:R-DME-2730847] Hydrolysis of PIP2 by PLCG - Drosophila melanogaster [Reaction:R-GGA-2730847] Hydrolysis of PIP2 by PLCG - Gallus gallus [Reaction:R-XTR-2730847] Hydrolysis of PIP2 by PLCG - Xenopus tropicalis [Reaction:R-SSC-2730847] Hydrolysis of PIP2 by PLCG - Sus scrofa [Reaction:R-BTA-2730847] Hydrolysis of PIP2 by PLCG - Bos taurus [Reaction:R-CFA-2730847] Hydrolysis of PIP2 by PLCG - Canis familiaris [Reaction:R-RNO-2730847] Hydrolysis of PIP2 by PLCG - Rattus norvegicus [Reaction:R-MMU-2730847] Hydrolysis of PIP2 by PLCG - Mus musculus [Reaction:R-HSA-2730847] Hydrolysis of PIP2 by PLCG - Homo sapiens [Reaction:R-RNO-182061] Active Plcg1 hydrolyses PIP2 - Rattus norvegicus [Reaction:R-HSA-202407] PLC-gamma1 hydrolyses PIP2 - Homo sapiens [Reaction:R-MMU-202407] PLC-gamma1 hydrolyses PIP2 - Mus musculus [Reaction:R-RNO-202407] PLC-gamma1 hydrolyses PIP2 - Rattus norvegicus [Reaction:R-CFA-202407] PLC-gamma1 hydrolyses PIP2 - Canis familiaris [Reaction:R-BTA-202407] PLC-gamma1 hydrolyses PIP2 - Bos taurus [Reaction:R-SSC-202407] PLC-gamma1 hydrolyses PIP2 - Sus scrofa [Reaction:R-DRE-202407] PLC-gamma1 hydrolyses PIP2 - Danio rerio [Reaction:R-XTR-202407] PLC-gamma1 hydrolyses PIP2 - Xenopus tropicalis [Reaction:R-GGA-202407] PLC-gamma1 hydrolyses PIP2 - Gallus gallus [Reaction:R-DME-202407] PLC-gamma1 hydrolyses PIP2 - Drosophila melanogaster [Reaction:R-CEL-202407] PLC-gamma1 hydrolyses PIP2 - Caenorhabditis elegans [Reaction:R-DDI-202407] PLC-gamma1 hydrolyses PIP2 - Dictyostelium discoideum [Reaction:R-SPO-202407] PLC-gamma1 hydrolyses PIP2 - Schizosaccharomyces pombe [Reaction:R-SCE-202407] PLC-gamma1 hydrolyses PIP2 - Saccharomyces cerevisiae [Reaction:R-PFA-202407] PLC-gamma1 hydrolyses PIP2 - Plasmodium falciparum [Reaction:R-HSA-111879] PIP2 hydrolysis - Homo sapiens [Reaction:R-MMU-111879] PIP2 hydrolysis - Mus musculus [Reaction:R-RNO-111879] PIP2 hydrolysis - Rattus norvegicus [Reaction:R-CFA-111879] PIP2 hydrolysis - Canis familiaris [Reaction:R-BTA-111879] PIP2 hydrolysis - Bos taurus [Reaction:R-SSC-111879] PIP2 hydrolysis - Sus scrofa [Reaction:R-DRE-111879] PIP2 hydrolysis - Danio rerio [Reaction:R-XTR-111879] PIP2 hydrolysis - Xenopus tropicalis [Reaction:R-GGA-111879] PIP2 hydrolysis - Gallus gallus [Reaction:R-DME-111879] PIP2 hydrolysis - Drosophila melanogaster [Reaction:R-CEL-111879] PIP2 hydrolysis - Caenorhabditis elegans [Reaction:R-DDI-111879] PIP2 hydrolysis - Dictyostelium discoideum [Reaction:R-RNO-622387] PIP2 hydrolysis - Rattus norvegicus [Reaction:R-HSA-622382] PIP2 hydrolysis - Homo sapiens [Reaction:R-MMU-2029468] Conversion of PA into DAG by PAP-1 - Mus musculus [Reaction:R-HSA-2029468] Conversion of PA into DAG by PAP-1 - Homo sapiens [Reaction:R-RNO-2029468] Conversion of PA into DAG by PAP-1 - Rattus norvegicus [Reaction:R-CFA-2029468] Conversion of PA into DAG by PAP-1 - Canis familiaris [Reaction:R-BTA-2029468] Conversion of PA into DAG by PAP-1 - Bos taurus [Reaction:R-SSC-2029468] Conversion of PA into DAG by PAP-1 - Sus scrofa [Reaction:R-XTR-2029468] Conversion of PA into DAG by PAP-1 - Xenopus tropicalis [Reaction:R-GGA-2029468] Conversion of PA into DAG by PAP-1 - Gallus gallus [Reaction:R-DME-2029468] Conversion of PA into DAG by PAP-1 - Drosophila melanogaster [Reaction:R-DDI-2029468] Conversion of PA into DAG by PAP-1 - Dictyostelium discoideum [Reaction:R-SPO-2029468] Conversion of PA into DAG by PAP-1 - Schizosaccharomyces pombe [Reaction:R-SCE-2029468] Conversion of PA into DAG by PAP-1 - Saccharomyces cerevisiae
referenceEntity	[ReferenceMolecule:chebi:18035] diglyceride [ChEBI:18035]
referenceType	ReferenceMolecule
schemaClass	SimpleEntity
stId	R-ALL-112275
updateTrackers	[UpdateTracker:9866609] Update Tracker - [SimpleEntity:112275] DAGs [plasma membrane] - v24:[addReferenceEntity] [UpdateTracker:9874250] Update Tracker - [SimpleEntity:112275] DAGs [plasma membrane] - v43:[addName] [UpdateTracker:9868238] Update Tracker - [SimpleEntity:112275] DAGs [plasma membrane] - v30:[modifyName] [UpdateTracker:9891794] Update Tracker - [SimpleEntity:112275] DAGs [plasma membrane] - v52:[addName]

Referrals

(hasComponent)	[Complex:R-MMU-2685677] RasGRP1:DAG:Ca2+ [plasma membrane] [Complex:R-HSA-2685686] RasGRPs:DAG:Ca2+ [plasma membrane] [Complex:R-CFA-5218773] DAG:active PKC:Ca+2 [plasma membrane] [Complex:R-GGA-5218773] DAG:active PKC:Ca+2 [plasma membrane] [Complex:R-SCE-5218773] DAG:active PKC:Ca+2 [plasma membrane] [Complex:R-SSC-5218773] DAG:active PKC:Ca+2 [plasma membrane] [Complex:R-BTA-5218773] DAG:active PKC:Ca+2 [plasma membrane] [Complex:R-MMU-5218773] DAG:active PKC:Ca+2 [plasma membrane] [Complex:R-DME-5218773] DAG:active PKC:Ca+2 [plasma membrane] [Complex:R-RNO-5218773] DAG:active PKC:Ca+2 [plasma membrane] [Complex:R-SPO-5218773] DAG:active PKC:Ca+2 [plasma membrane] [Complex:R-XTR-5218773] DAG:active PKC:Ca+2 [plasma membrane] [Complex:R-CEL-5218773] DAG:active PKC:Ca+2 [plasma membrane] [Complex:R-DRE-5218773] DAG:active PKC:Ca+2 [plasma membrane] [Complex:R-DDI-5218773] DAG:active PKC:Ca+2 [plasma membrane] [Complex:R-HSA-5218773] DAG:active PKC:Ca+2 [plasma membrane] [Complex:R-DDI-5607700] DAGs:p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-DRE-5607700] DAGs:p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-BTA-5607700] DAGs:p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-RNO-5607700] DAGs:p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-SPO-5607700] DAGs:p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-DME-5607700] DAGs:p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-CFA-5607700] DAGs:p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-XTR-5607700] DAGs:p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-SSC-5607700] DAGs:p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-GGA-5607700] DAGs:p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-MMU-5607700] DAGs:p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-CEL-5607700] DAGs:p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-SCE-5607700] DAGs:p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-HSA-5607700] DAGs:p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-CFA-202442] Active PKC theta bound to DAG [plasma membrane] [Complex:R-BTA-202442] Active PKC theta bound to DAG [plasma membrane] [Complex:R-RNO-202442] Active PKC theta bound to DAG [plasma membrane] [Complex:R-MMU-202442] Active PKC theta bound to DAG [plasma membrane] [Complex:R-SCE-202442] Active PKC theta bound to DAG [plasma membrane] [Complex:R-SPO-202442] Active PKC theta bound to DAG [plasma membrane] [Complex:R-SSC-202442] Active PKC theta bound to DAG [plasma membrane] [Complex:R-CEL-202442] Active PKC theta bound to DAG [plasma membrane] [Complex:R-DDI-202442] Active PKC theta bound to DAG [plasma membrane] [Complex:R-GGA-202442] Active PKC theta bound to DAG [plasma membrane] [Complex:R-DME-202442] Active PKC theta bound to DAG [plasma membrane] [Complex:R-HSA-202442] Active PKC theta bound to DAG [plasma membrane] [Complex:R-SCE-202187] PKC-theta (open): DAG [plasma membrane] [Complex:R-DME-202187] PKC-theta (open): DAG [plasma membrane] [Complex:R-CFA-202187] PKC-theta (open): DAG [plasma membrane] [Complex:R-CEL-202187] PKC-theta (open): DAG [plasma membrane] [Complex:R-GGA-202187] PKC-theta (open): DAG [plasma membrane] [Complex:R-DDI-202187] PKC-theta (open): DAG [plasma membrane] [Complex:R-SSC-202187] PKC-theta (open): DAG [plasma membrane] [Complex:R-BTA-202187] PKC-theta (open): DAG [plasma membrane] [Complex:R-RNO-202187] PKC-theta (open): DAG [plasma membrane] [Complex:R-MMU-202187] PKC-theta (open): DAG [plasma membrane] [Complex:R-SPO-202187] PKC-theta (open): DAG [plasma membrane] [Complex:R-HSA-202187] PKC-theta (open): DAG [plasma membrane] [Complex:R-SSC-202300] p-Y90-PKC-theta:DAG [plasma membrane] [Complex:R-SPO-202300] p-Y90-PKC-theta:DAG [plasma membrane] [Complex:R-CEL-202300] p-Y90-PKC-theta:DAG [plasma membrane] [Complex:R-DME-202300] p-Y90-PKC-theta:DAG [plasma membrane] [Complex:R-CFA-202300] p-Y90-PKC-theta:DAG [plasma membrane] [Complex:R-GGA-202300] p-Y90-PKC-theta:DAG [plasma membrane] [Complex:R-RNO-202300] p-Y90-PKC-theta:DAG [plasma membrane] [Complex:R-MMU-202300] p-Y90-PKC-theta:DAG [plasma membrane] [Complex:R-DDI-202300] p-Y90-PKC-theta:DAG [plasma membrane] [Complex:R-BTA-202300] p-Y90-PKC-theta:DAG [plasma membrane] [Complex:R-SCE-202300] p-Y90-PKC-theta:DAG [plasma membrane] [Complex:R-HSA-202300] p-Y90-PKC-theta:DAG [plasma membrane] [Complex:R-DRE-5607689] DAGs:active p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-SCE-5607689] DAGs:active p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-DME-5607689] DAGs:active p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-CFA-5607689] DAGs:active p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-SSC-5607689] DAGs:active p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-DDI-5607689] DAGs:active p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-GGA-5607689] DAGs:active p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-XTR-5607689] DAGs:active p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-CEL-5607689] DAGs:active p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-MMU-5607689] DAGs:active p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-SPO-5607689] DAGs:active p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-RNO-5607689] DAGs:active p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-BTA-5607689] DAGs:active p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-HSA-5607689] DAGs:active p-T507,S645,S664-PRKCD [plasma membrane] [Complex:R-SSC-8934445] DAGs:active p-T566,T710,S729-PRKCE [plasma membrane] [Complex:R-DME-8934445] DAGs:active p-T566,T710,S729-PRKCE [plasma membrane] [Complex:R-RNO-8934445] DAGs:active p-T566,T710,S729-PRKCE [plasma membrane] [Complex:R-MMU-8934445] DAGs:active p-T566,T710,S729-PRKCE [plasma membrane] [Complex:R-CFA-8934445] DAGs:active p-T566,T710,S729-PRKCE [plasma membrane] [Complex:R-HSA-8934445] DAGs:active p-T566,T710,S729-PRKCE [plasma membrane] [Complex:R-SPO-2685674] p-5Y-PKC-theta:DAG [plasma membrane] [Complex:R-BTA-2685674] p-5Y-PKC-theta:DAG [plasma membrane] [Complex:R-CFA-2685674] p-5Y-PKC-theta:DAG [plasma membrane] [Complex:R-SCE-2685674] p-5Y-PKC-theta:DAG [plasma membrane] [Complex:R-GGA-2685674] p-5Y-PKC-theta:DAG [plasma membrane] [Complex:R-DDI-2685674] p-5Y-PKC-theta:DAG [plasma membrane] [Complex:R-CEL-2685674] p-5Y-PKC-theta:DAG [plasma membrane] [Complex:R-SSC-2685674] p-5Y-PKC-theta:DAG [plasma membrane] [Complex:R-DME-2685674] p-5Y-PKC-theta:DAG [plasma membrane] [Complex:R-XTR-2685674] p-5Y-PKC-theta:DAG [plasma membrane] [Complex:R-MMU-1169551] p-Rasgrp1,3:DAG [plasma membrane] [Complex:R-RNO-2685674] p-5Y-PKC-theta:DAG [plasma membrane] [Complex:R-HSA-2685674] p-5Y-PKC-theta:DAG [plasma membrane] [Complex:R-MMU-2685674] p-5Y-PKC-theta:DAG [plasma membrane]
(input)	[Reaction:R-MMU-2730865] RasGRP interacts with DAG and Ca2+ [Reaction:R-HSA-2730871] RasGRP interacts with DAG and Ca2+ [Reaction:R-SCE-5218813] DAG and Ca+2 bind to PKC and tether it to membrane [Reaction:R-SPO-5218813] DAG and Ca+2 bind to PKC and tether it to membrane [Reaction:R-DDI-5218813] DAG and Ca+2 bind to PKC and tether it to membrane [Reaction:R-CEL-5218813] DAG and Ca+2 bind to PKC and tether it to membrane [Reaction:R-DME-5218813] DAG and Ca+2 bind to PKC and tether it to membrane [Reaction:R-GGA-5218813] DAG and Ca+2 bind to PKC and tether it to membrane [Reaction:R-XTR-5218813] DAG and Ca+2 bind to PKC and tether it to membrane [Reaction:R-DRE-5218813] DAG and Ca+2 bind to PKC and tether it to membrane [Reaction:R-SSC-5218813] DAG and Ca+2 bind to PKC and tether it to membrane [Reaction:R-BTA-5218813] DAG and Ca+2 bind to PKC and tether it to membrane [Reaction:R-CFA-5218813] DAG and Ca+2 bind to PKC and tether it to membrane [Reaction:R-RNO-5218813] DAG and Ca+2 bind to PKC and tether it to membrane [Reaction:R-MMU-5218813] DAG and Ca+2 bind to PKC and tether it to membrane [Reaction:R-HSA-5218813] DAG and Ca+2 bind to PKC and tether it to membrane [Reaction:R-SCE-5607734] PKC-delta translocates to plasma membrane [Reaction:R-SPO-5607734] PKC-delta translocates to plasma membrane [Reaction:R-DDI-5607734] PKC-delta translocates to plasma membrane [Reaction:R-CEL-5607734] PKC-delta translocates to plasma membrane [Reaction:R-DME-5607734] PKC-delta translocates to plasma membrane [Reaction:R-GGA-5607734] PKC-delta translocates to plasma membrane [Reaction:R-XTR-5607734] PKC-delta translocates to plasma membrane [Reaction:R-DRE-5607734] PKC-delta translocates to plasma membrane [Reaction:R-SSC-5607734] PKC-delta translocates to plasma membrane [Reaction:R-BTA-5607734] PKC-delta translocates to plasma membrane [Reaction:R-CFA-5607734] PKC-delta translocates to plasma membrane [Reaction:R-RNO-5607734] PKC-delta translocates to plasma membrane [Reaction:R-MMU-5607734] PKC-delta translocates to plasma membrane [Reaction:R-HSA-5607734] PKC-delta translocates to plasma membrane [Reaction:R-SCE-202328] Translocation of PKC theta to plasma membrane [Reaction:R-SPO-202328] Translocation of PKC theta to plasma membrane [Reaction:R-DDI-202328] Translocation of PKC theta to plasma membrane [Reaction:R-CEL-202328] Translocation of PKC theta to plasma membrane [Reaction:R-DME-202328] Translocation of PKC theta to plasma membrane [Reaction:R-GGA-202328] Translocation of PKC theta to plasma membrane [Reaction:R-SSC-202328] Translocation of PKC theta to plasma membrane [Reaction:R-BTA-202328] Translocation of PKC theta to plasma membrane [Reaction:R-CFA-202328] Translocation of PKC theta to plasma membrane [Reaction:R-RNO-202328] Translocation of PKC theta to plasma membrane [Reaction:R-MMU-202328] Translocation of PKC theta to plasma membrane [Reaction:R-HSA-202328] Translocation of PKC theta to plasma membrane [BlackBoxEvent:R-MMU-1169494] Rasgrp1 and Rasgrp3 are recruited to the membrane and phosphorylated
(output)	[Reaction:R-MMU-9032476] Epor-associated Plcg hydrolyzes 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate [Reaction:R-HSA-9032478] EPOR-associated PLCG hydrolyzes 1-Phosphatidyl-1D-myo-inositol 4,5-bisphosphate [Reaction:R-HSA-9680388] CSF1R-associated PLCG2 hydrolyzes phosphatidylcholine [Reaction:R-RNO-622387] PIP2 hydrolysis [Reaction:R-HSA-622382] PIP2 hydrolysis [Reaction:R-PFA-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 [Reaction:R-SCE-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 [Reaction:R-SPO-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 [Reaction:R-DDI-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 [Reaction:R-CEL-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 [Reaction:R-DME-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 [Reaction:R-GGA-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 [Reaction:R-XTR-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 [Reaction:R-SSC-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 [Reaction:R-BTA-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 [Reaction:R-CFA-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 [Reaction:R-RNO-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 [Reaction:R-MMU-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 [Reaction:R-HSA-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 [Reaction:R-DME-2730847] Hydrolysis of PIP2 by PLCG [Reaction:R-GGA-2730847] Hydrolysis of PIP2 by PLCG [Reaction:R-XTR-2730847] Hydrolysis of PIP2 by PLCG [Reaction:R-SSC-2730847] Hydrolysis of PIP2 by PLCG [Reaction:R-BTA-2730847] Hydrolysis of PIP2 by PLCG [Reaction:R-CFA-2730847] Hydrolysis of PIP2 by PLCG [Reaction:R-RNO-2730847] Hydrolysis of PIP2 by PLCG [Reaction:R-MMU-2730847] Hydrolysis of PIP2 by PLCG [Reaction:R-HSA-2730847] Hydrolysis of PIP2 by PLCG [Reaction:R-RNO-182061] Active Plcg1 hydrolyses PIP2 [Reaction:R-HSA-202407] PLC-gamma1 hydrolyses PIP2 [Reaction:R-MMU-202407] PLC-gamma1 hydrolyses PIP2 [Reaction:R-RNO-202407] PLC-gamma1 hydrolyses PIP2 [Reaction:R-CFA-202407] PLC-gamma1 hydrolyses PIP2 [Reaction:R-BTA-202407] PLC-gamma1 hydrolyses PIP2 [Reaction:R-SSC-202407] PLC-gamma1 hydrolyses PIP2 [Reaction:R-DRE-202407] PLC-gamma1 hydrolyses PIP2 [Reaction:R-XTR-202407] PLC-gamma1 hydrolyses PIP2 [Reaction:R-GGA-202407] PLC-gamma1 hydrolyses PIP2 [Reaction:R-DME-202407] PLC-gamma1 hydrolyses PIP2 [Reaction:R-CEL-202407] PLC-gamma1 hydrolyses PIP2 [Reaction:R-DDI-202407] PLC-gamma1 hydrolyses PIP2 [Reaction:R-SPO-202407] PLC-gamma1 hydrolyses PIP2 [Reaction:R-SCE-202407] PLC-gamma1 hydrolyses PIP2 [Reaction:R-PFA-202407] PLC-gamma1 hydrolyses PIP2 [Reaction:R-HSA-111879] PIP2 hydrolysis [Reaction:R-MMU-111879] PIP2 hydrolysis [Reaction:R-RNO-111879] PIP2 hydrolysis [Reaction:R-CFA-111879] PIP2 hydrolysis [Reaction:R-BTA-111879] PIP2 hydrolysis [Reaction:R-SSC-111879] PIP2 hydrolysis [Reaction:R-DRE-111879] PIP2 hydrolysis [Reaction:R-XTR-111879] PIP2 hydrolysis [Reaction:R-GGA-111879] PIP2 hydrolysis [Reaction:R-DME-111879] PIP2 hydrolysis [Reaction:R-CEL-111879] PIP2 hydrolysis [Reaction:R-DDI-111879] PIP2 hydrolysis [Reaction:R-MMU-2029468] Conversion of PA into DAG by PAP-1 [Reaction:R-HSA-2029468] Conversion of PA into DAG by PAP-1 [Reaction:R-RNO-2029468] Conversion of PA into DAG by PAP-1 [Reaction:R-CFA-2029468] Conversion of PA into DAG by PAP-1 [Reaction:R-BTA-2029468] Conversion of PA into DAG by PAP-1 [Reaction:R-SSC-2029468] Conversion of PA into DAG by PAP-1 [Reaction:R-XTR-2029468] Conversion of PA into DAG by PAP-1 [Reaction:R-GGA-2029468] Conversion of PA into DAG by PAP-1 [Reaction:R-DME-2029468] Conversion of PA into DAG by PAP-1 [Reaction:R-DDI-2029468] Conversion of PA into DAG by PAP-1 [Reaction:R-SPO-2029468] Conversion of PA into DAG by PAP-1 [Reaction:R-SCE-2029468] Conversion of PA into DAG by PAP-1
(regulator)	[PositiveRegulation:R-XLA-8855329] Positive regulation by 'DAGs [plasma membrane]' [PositiveRegulation:R-HSA-8855331] Positive regulation by 'DAGs [plasma membrane]'
(requiredInputComponent)	[Reaction:R-HSA-5218805] PKC autophosphorylates
(updatedInstance)	[UpdateTracker:9866609] Update Tracker - [SimpleEntity:112275] DAGs [plasma membrane] - v24:[addReferenceEntity] [UpdateTracker:9874250] Update Tracker - [SimpleEntity:112275] DAGs [plasma membrane] - v43:[addName] [UpdateTracker:9868238] Update Tracker - [SimpleEntity:112275] DAGs [plasma membrane] - v30:[modifyName] [UpdateTracker:9891794] Update Tracker - [SimpleEntity:112275] DAGs [plasma membrane] - v52:[addName]

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