Reactome | Translocation of PKC theta to plasma membrane

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Translocation of PKC theta to plasma membrane Show undefined attributes

authored	[InstanceEdit:211006] Rudd, C.E., de Bono, B, Garapati, P V, 2008-01-24 15:53:10
category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:202250] Garapati, P V, 2007-10-29 14:08:25
dbId	202328
deleted	[Deleted:8875149] Deletion of instance: 2730875
displayName	Translocation of PKC theta to plasma membrane
eventOf	[Pathway:R-HSA-2871837] FCERI mediated NF-kB activation - Homo sapiens [Pathway:R-HSA-202424] Downstream TCR signaling - Homo sapiens
followingEvent	[Reaction:R-HSA-202307] Change of PKC theta conformation - Homo sapiens [Reaction:R-HSA-2730882] Phosphorylation of PKC-theta - Homo sapiens
input	[SimpleEntity:R-ALL-112275] DAGs [plasma membrane] [EntityWithAccessionedSequence:R-HSA-202185] PRKQC closed conformation [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:202301] Selective function of PKC-theta in T cells [LiteratureReference:202369] Protein kinase C-theta (PKC theta): a key enzyme in T cell life and death [LiteratureReference:2685371] Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Ctheta [LiteratureReference:2685257] Protein kinase C theta is expressed in mast cells and is functionally involved in Fcepsilon receptor I signaling
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	Translocation of PKC theta to plasma membrane
orthologousEvent	[Reaction:R-SCE-202328] Translocation of PKC theta to plasma membrane - Saccharomyces cerevisiae [Reaction:R-SPO-202328] Translocation of PKC theta to plasma membrane - Schizosaccharomyces pombe [Reaction:R-DDI-202328] Translocation of PKC theta to plasma membrane - Dictyostelium discoideum [Reaction:R-CEL-202328] Translocation of PKC theta to plasma membrane - Caenorhabditis elegans [Reaction:R-DME-202328] Translocation of PKC theta to plasma membrane - Drosophila melanogaster [Reaction:R-GGA-202328] Translocation of PKC theta to plasma membrane - Gallus gallus [Reaction:R-SSC-202328] Translocation of PKC theta to plasma membrane - Sus scrofa [Reaction:R-BTA-202328] Translocation of PKC theta to plasma membrane - Bos taurus [Reaction:R-CFA-202328] Translocation of PKC theta to plasma membrane - Canis familiaris [Reaction:R-RNO-202328] Translocation of PKC theta to plasma membrane - Rattus norvegicus [Reaction:R-MMU-202328] Translocation of PKC theta to plasma membrane - Mus musculus
output	[Complex:R-HSA-202187] PKC-theta (open): DAG [plasma membrane]
precedingEvent	[Reaction:R-HSA-202164] Translocation of PDK1 to Plasma membrane - Homo sapiens [Reaction:R-HSA-2730847] Hydrolysis of PIP2 by PLCG - Homo sapiens
releaseDate	2008-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:214481] Trowsdale, J, 2008-02-26 12:02:59
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-202328
summation	[Summation:202380] DAG along with intracellular calcium signals cooperatively t...
updateTrackers	[UpdateTracker:9783128] Update Tracker - [Reaction:202328] Translocation of PKC theta to plasma membrane - v57:[addLiteratureReference, modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9783128] Update Tracker - [Reaction:202328] Translocation of PKC theta to plasma membrane - v57:[addLiteratureReference, modifyText]
(replacementInstances)	[Deleted:8875149] Deletion of instance: 2730875
(hasEvent)	[Pathway:R-HSA-2871837] FCERI mediated NF-kB activation [Pathway:R-HSA-202424] Downstream TCR signaling
(precedingEvent)	[Reaction:R-HSA-202307] Change of PKC theta conformation [Reaction:R-HSA-2730882] Phosphorylation of PKC-theta

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