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Schema
>
CatalystActivity
>
Entries
endopeptidase activity of 26S proteasome [cytosol]
Show undefined attributes
activity
[GO_MolecularFunction:1793] endopeptidase activity
catalyzedEvent
[BlackBoxEvent:R-XTR-5687112] MAPK6 is degraded by the 26S proteasome - Xenopus tropicalis
[BlackBoxEvent:R-XTR-450466] AUF1:mRNA complex is degraded - Xenopus tropicalis
[BlackBoxEvent:R-XTR-9954728] The proteasome degrades the K48-polyubiquitinated alanine-tailed nascent peptide - Xenopus tropicalis
[BlackBoxEvent:R-XTR-9755303] 26S proteasome degrades HIFalpha - Xenopus tropicalis
[BlackBoxEvent:R-XTR-5668520] 26Sproteasome degrades K48polyUb-NIK - Xenopus tropicalis
[BlackBoxEvent:R-XTR-5362448] Hh C-terminal fragments are degraded by the proteasome - Xenopus tropicalis
[BlackBoxEvent:R-XTR-9934893] Proteolysis of K48polyUb-K,p-S-PER1,2,3 - Xenopus tropicalis
[BlackBoxEvent:R-XTR-9755306] ub UBXN7 is degraded by the 26S proteasome - Xenopus tropicalis
[BlackBoxEvent:R-XTR-8866553] misfolded CFTR is degraded by the 26S proteasome - Xenopus tropicalis
[BlackBoxEvent:R-XTR-8932355] 26S proteasome degrades Ub-NFE2L2 - Xenopus tropicalis
[BlackBoxEvent:R-XTR-8957265] 26S proteasome degrades TP73 polyubiquitinated by ITCH - Xenopus tropicalis
[BlackBoxEvent:R-XTR-5610760] GLI1 is degraded by the proteasome after ubiquitination by ITCH - Xenopus tropicalis
[BlackBoxEvent:R-XTR-5610758] GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP - Xenopus tropicalis
[BlackBoxEvent:R-XTR-5635868] ub-GLI is degraded by the proteasome - Xenopus tropicalis
[BlackBoxEvent:R-XTR-5668481] Protesomal degradation of K48polyUb-TRAF3 - Xenopus tropicalis
[BlackBoxEvent:R-XTR-5607731] 26S proteasome processes p-7S-p100:RELB to form p52:RELB - Xenopus tropicalis
[BlackBoxEvent:R-XTR-1236970] Proteasomal clevage of exogenous antigen (26S proteasome catalyst) - Xenopus tropicalis
[BlackBoxEvent:R-XTR-353125] 26S proteosome degrades ODC holoenzyme complex - Xenopus tropicalis
[Reaction:R-XTR-9929486] SPOP-mediated degradation of CD274 by 26S Proteosome - Xenopus tropicalis
[BlackBoxEvent:R-XTR-75825] Proteasome mediated degradation of Cyclin D1 - Xenopus tropicalis
[BlackBoxEvent:R-XTR-1168640] Ubiquitinated IkB is degraded - Xenopus tropicalis
[BlackBoxEvent:R-XTR-69016] Ubiquitinated Cdc6 is degraded by the proteasome - Xenopus tropicalis
[BlackBoxEvent:R-XTR-5610754] GLI3 is partially degraded by the proteasome to yield the GLI3 repressor - Xenopus tropicalis
[BlackBoxEvent:R-XTR-9766223] Proteasome-dependent degradation of ubiquitinated CDH1 - Xenopus tropicalis
[BlackBoxEvent:R-XTR-2130282] Degradation of ubiquitinated beta catenin by the proteasome - Xenopus tropicalis
[BlackBoxEvent:R-XTR-4641256] Ubiquitinated AXIN is degraded by the proteasome - Xenopus tropicalis
[BlackBoxEvent:R-XTR-4608855] PRICKLE1 is degraded by the proteasome - Xenopus tropicalis
[BlackBoxEvent:R-XTR-68948] Ubiquitinated Orc1 is degraded by the proteasome - Xenopus tropicalis
[BlackBoxEvent:R-XTR-1234159] Proteasome proteolyzes ub-HIF-alpha - Xenopus tropicalis
[BlackBoxEvent:R-XTR-8850992] Proteasome degrades polyubiquitinated PTEN - Xenopus tropicalis
[BlackBoxEvent:R-XTR-983150] Proteasomal cleavage of substrate - Xenopus tropicalis
[BlackBoxEvent:R-XTR-8852354] GTSE1 facilitates proteasome-mediated degradation of TP53 - Xenopus tropicalis
[BlackBoxEvent:R-XTR-264458] Proteasome mediated degradation of COP1 - Xenopus tropicalis
[BlackBoxEvent:R-XTR-174105] Degradation of multiubiquitinated cell cycle proteins - Xenopus tropicalis
[BlackBoxEvent:R-XTR-174202] Degradation of multiubiquitinated Securin - Xenopus tropicalis
[BlackBoxEvent:R-XTR-174255] Degradation multiubiquitinated Cyclin A - Xenopus tropicalis
created
[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId
10652009
displayName
endopeptidase activity of 26S proteasome [cytosol]
physicalEntity
[Complex:R-XTR-68819] 26S proteasome [cytosol]
schemaClass
CatalystActivity
Referrals
(catalystActivity)
[BlackBoxEvent:R-XTR-5687112] MAPK6 is degraded by the 26S proteasome
[BlackBoxEvent:R-XTR-450466] AUF1:mRNA complex is degraded
[BlackBoxEvent:R-XTR-9954728] The proteasome degrades the K48-polyubiquitinated alanine-tailed nascent peptide
[BlackBoxEvent:R-XTR-9755303] 26S proteasome degrades HIFalpha
[BlackBoxEvent:R-XTR-5668520] 26Sproteasome degrades K48polyUb-NIK
[BlackBoxEvent:R-XTR-5362448] Hh C-terminal fragments are degraded by the proteasome
[BlackBoxEvent:R-XTR-9934893] Proteolysis of K48polyUb-K,p-S-PER1,2,3
[BlackBoxEvent:R-XTR-9755306] ub UBXN7 is degraded by the 26S proteasome
[BlackBoxEvent:R-XTR-8866553] misfolded CFTR is degraded by the 26S proteasome
[BlackBoxEvent:R-XTR-8932355] 26S proteasome degrades Ub-NFE2L2
[BlackBoxEvent:R-XTR-8957265] 26S proteasome degrades TP73 polyubiquitinated by ITCH
[BlackBoxEvent:R-XTR-5610760] GLI1 is degraded by the proteasome after ubiquitination by ITCH
[BlackBoxEvent:R-XTR-5610758] GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP
[BlackBoxEvent:R-XTR-5635868] ub-GLI is degraded by the proteasome
[BlackBoxEvent:R-XTR-5668481] Protesomal degradation of K48polyUb-TRAF3
[BlackBoxEvent:R-XTR-5607731] 26S proteasome processes p-7S-p100:RELB to form p52:RELB
[BlackBoxEvent:R-XTR-1236970] Proteasomal clevage of exogenous antigen (26S proteasome catalyst)
[BlackBoxEvent:R-XTR-353125] 26S proteosome degrades ODC holoenzyme complex
[Reaction:R-XTR-9929486] SPOP-mediated degradation of CD274 by 26S Proteosome
[BlackBoxEvent:R-XTR-75825] Proteasome mediated degradation of Cyclin D1
[BlackBoxEvent:R-XTR-1168640] Ubiquitinated IkB is degraded
[BlackBoxEvent:R-XTR-69016] Ubiquitinated Cdc6 is degraded by the proteasome
[BlackBoxEvent:R-XTR-5610754] GLI3 is partially degraded by the proteasome to yield the GLI3 repressor
[BlackBoxEvent:R-XTR-9766223] Proteasome-dependent degradation of ubiquitinated CDH1
[BlackBoxEvent:R-XTR-2130282] Degradation of ubiquitinated beta catenin by the proteasome
[BlackBoxEvent:R-XTR-4641256] Ubiquitinated AXIN is degraded by the proteasome
[BlackBoxEvent:R-XTR-4608855] PRICKLE1 is degraded by the proteasome
[BlackBoxEvent:R-XTR-68948] Ubiquitinated Orc1 is degraded by the proteasome
[BlackBoxEvent:R-XTR-1234159] Proteasome proteolyzes ub-HIF-alpha
[BlackBoxEvent:R-XTR-8850992] Proteasome degrades polyubiquitinated PTEN
[BlackBoxEvent:R-XTR-983150] Proteasomal cleavage of substrate
[BlackBoxEvent:R-XTR-8852354] GTSE1 facilitates proteasome-mediated degradation of TP53
[BlackBoxEvent:R-XTR-264458] Proteasome mediated degradation of COP1
[BlackBoxEvent:R-XTR-174105] Degradation of multiubiquitinated cell cycle proteins
[BlackBoxEvent:R-XTR-174202] Degradation of multiubiquitinated Securin
[BlackBoxEvent:R-XTR-174255] Degradation multiubiquitinated Cyclin A
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