Reactome | 26S proteasome [cytosol]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10652009] endopeptidase activity of 26S proteasome [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-XTR-5665858] ADRM1:26S proteasome [cytosol] - Xenopus tropicalis [Complex:R-XTR-8956137] NEDD8,UBD:NUB1:26S proteasome [cytosol] - Xenopus tropicalis
consumedByEvent	[Reaction:R-XTR-8956140] NEDD8 and UBD bind NUB1 and the 26S proteasome - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10652008
displayName	26S proteasome [cytosol]
hasComponent	[Complex:R-XTR-9908177] 19S regulatory particle [cytosol] [Complex:R-XTR-9907918] 20S core particle [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-68819] 26S proteasome [cytosol] - Homo sapiens
maxDepth	7
name	26S proteasome
producedByEvent	[BlackBoxEvent:R-XTR-8956184] 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates - Xenopus tropicalis
schemaClass	Complex
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-68819
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasComponent)	[Complex:R-XTR-5665858] ADRM1:26S proteasome [cytosol] [Complex:R-XTR-8956137] NEDD8,UBD:NUB1:26S proteasome [cytosol]
(output)	[BlackBoxEvent:R-XTR-8956184] 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates
(input)	[Reaction:R-XTR-8956140] NEDD8 and UBD bind NUB1 and the 26S proteasome
(physicalEntity)	[CatalystActivity:10652009] endopeptidase activity of 26S proteasome [cytosol]
(inferredTo)	[Complex:R-HSA-68819] 26S proteasome [cytosol]