Reactome | PRICKLE1 is degraded by the proteasome

Schema > BlackBoxEvent > Entries

catalystActivity	[CatalystActivity:10652009] endopeptidase activity of 26S proteasome [cytosol]
category	omitted
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10695329
displayName	PRICKLE1 is degraded by the proteasome
eventOf	[Pathway:R-XTR-4608870] Asymmetric localization of PCP proteins - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-4608855] PRICKLE1 is degraded by the proteasome - Homo sapiens
input	[EntityWithAccessionedSequence:R-XTR-4608820] prickle1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PRICKLE1 is degraded by the proteasome
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-4608855
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-XTR-4608870] Asymmetric localization of PCP proteins
(inferredTo)	[BlackBoxEvent:R-HSA-4608855] PRICKLE1 is degraded by the proteasome

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