Reactome | PELO [cytosol]

PELO [cytosol]

Stable Identifier

R-HSA-9954712

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

fullName evidence="13"Protein pelota homolog, PELO_HUMAN

Locations in the PathwayBrowser for interactor UniProt:O00165 HAX1

Expand all

External Reference Information

External Reference

UniProt:Q9BRX2 PELO

Gene Names

PELO, CGI-17

Chain

chain:1-385

Reference Genes

BioGPS Gene:53918 PELO

COSMIC - genes:PELO PELO

CTD Gene:53918 PELO

dbSNP Gene:53918 PELO

ENSEMBL:ENSG00000152684 PELO

HGNC:8829 PELO

KEGG:hsa:53918 PELO

Monarch:53918 PELO

NCBI Gene:53918 PELO

OMIM:605757 PELO

UCSC:Q9BRX2 PELO

Reference Transcript

RefSeq:NM_015946.4 PELO

Other Identifiers

11719917_at

11719918_s_at

1553140_PM_at

1553140_at

218472_PM_s_at

218472_s_at

2809129

2809130

2809136

2809137

2809138

2809139

2809140

2809141

2809142

2809143

2809144

2809145

2809146

2809147

2809148

2809149

2809150

53918

57628_at

69325_at

8105229

A_14_P118230

A_14_P124515

A_23_P58763

A_24_P66239

GE58622

GO:0001833

GO:0005515

GO:0005737

GO:0005840

GO:0006417

GO:0007492

GO:0016071

GO:0019827

GO:0022626

GO:0030154

GO:0030513

GO:0032790

GO:0043022

GO:0046872

GO:0048856

GO:0051276

GO:0051301

GO:0060231

GO:0060589

GO:0070481

GO:0070651

GO:0070966

GO:0071025

GO:0072344

GO:0098772

GO:0140299

GO:0170011

GO:1990533

HMNXSV003003508

Hs2.196972.1.A1_3p_at

ILMN_1770811

PH_hs_0025010

TC05003438.hg

g7705599_3p_s_at

Participates

as an output of

ABCE1:PELO:80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide dissociates yielding ABCE1:40S ribosomal subunit, PELO, and 60S ribosomal subunit:peptidyl-tRNA with nascent peptide (Homo sapiens)

as a component of

Inferred To

pelo [cytosol] (Danio rerio)

pelo [cytosol] (Dictyostelium discoideum)

pelo [cytosol] (Drosophila melanogaster)

pelo [cytosol] (Xenopus tropicalis)

dom34 [cytosol] (Schizosaccharomyces pombe)

Pelo [cytosol] (Mus musculus)

Pelo [cytosol] (Rattus norvegicus)

DOM34 [cytosol] (Saccharomyces cerevisiae)

pelo-1 [cytosol] (Caenorhabditis elegans)

Ghost homologue of PELO [cytosol] (Canis familiaris)

PELO [cytosol] (Bos taurus)

PELO [cytosol] (Gallus gallus)

PELO [cytosol] (Plasmodium falciparum)

PELO [cytosol] (Sus scrofa)

Cross References

RefSeq

NP_057030.3

OpenTargets

ENSG00000152684

ENSEMBL

ENSP00000274311, ENSG00000152684, ENST00000274311

HPA

ENSG00000152684-PELO

GeneCards

PELO

PRO

Q9BRX2

Pharos - Targets

Q9BRX2

PDB

5EO3, 1X52, 5LZX, 5LZW, 5LZY, 5LZZ

Interactors (29)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Y450 HBS1L	1	HBS1L [cytosol] (R-HSA-8931539)	0.781	7
UniProt:Q8TAP4-4 LMO3			0.718	9
UniProt:P21333-2 FLNA			0.718	6
UniProt:P04792 HSPB1	3	HSPB1 [cytosol] (R-HSA-450563) p-S15,S78,S82-HSP27 [cytosol] (R-HSA-5218697) p-S78,S82 HSPB1 [cytosol] (R-HSA-5687009)	0.666	4
UniProt:O00165 HAX1			0.66	7
UniProt:P78539 SRPX			0.65	6
UniProt:O75821 EIF3G	1	EIF3G [cytosol] (R-HSA-72538)	0.65	6
UniProt:P17252 PRKCA	8	PRKCA [cytosol] (R-HSA-58196) pT497,T638,S657-PRKCA [plasma membrane] (R-HSA-4332340) p-T497,T638,S657-PRKCA [cytosol] (R-HSA-4332337) PRKCA [plasma membrane] (R-HSA-156469) p-T497-PRKCA [cytosol] (R-HSA-5218731) p-T497,T638,S657-PRKCA [nucleoplasm] (R-HSA-5223292) PRKCA [photoreceptor disc membrane] (R-HSA-2648987) PRKCA [nucleoplasm] (R-HSA-450530)	0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	12
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.556	3
UniProt:P07196 NEFL	1	NEFL [cytosol] (R-HSA-432284)	0.556	3
UniProt:P61968 LMO4			0.556	3
UniProt:O95817 BAG3	1	BAG3 [cytosol] (R-HSA-5255451)	0.556	3
UniProt:Q15047-2 SETDB1			0.556	3
UniProt:Q6FHY5 Q6FHY5			0.556	3
UniProt:Q92993 KAT5	1	KAT5 [nucleoplasm] (R-HSA-3321979)	0.556	3
UniProt:P31153 MAT2A	1	MAT2A [cytosol] (R-HSA-174363)	0.556	3
UniProt:P05362 ICAM1	1	ICAM1 [plasma membrane] (R-HSA-197683)	0.556	3
UniProt:P60891 PRPS1	1	PRPS1 [cytosol] (R-HSA-73483)	0.556	3
UniProt:Q9HB07 MYG1			0.556	3
UniProt:O60333-2 KIF1B			0.556	3
UniProt:P62937-2 P629372			0.556	3
UniProt:P63172 DYNLT1	4	DYNLT1 [ficolin-1-rich granule lumen] (R-HSA-6801487) DYNLT1 [extracellular region] (R-HSA-6806509) DYNLT1 [secretory granule lumen] (R-HSA-6801497) DYNLT1 [cytosol] (R-HSA-6801602)	0.556	3
UniProt:P11362-2 FGFR1			0.556	3
UniProt:P59991 KRTAP12-2	1	KRTAP12-2 [cytosol] (R-HSA-6810271)	0.556	3
UniProt:Q92569 PIK3R3	2	PIK3R3 [cytosol] (R-HSA-205223) K63polyUb-PIK3R3 [cytosol] (R-HSA-3080574)	0.488	2
UniProt:Q8TC44 POC1B			0.483	2
UniProt:P03366 POL			0.462	2

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