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ICAM1 [plasma membrane]
Stable Identifier
R-HSA-197683
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Intercellular adhesion molecule-1 precursor, ICA1_HUMAN, CD54
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Integrin cell surface interactions (Homo sapiens)
ICAM1-5 bind Integrin alphaLbeta2 (LFA-1) (Homo sapiens)
ICAM 1-5 [plasma membrane] (Homo sapiens)
ICAM1 [plasma membrane] (Homo sapiens)
LFA-1:ICAM 1-5 [plasma membrane] (Homo sapiens)
ICAM 1-5 [plasma membrane] (Homo sapiens)
ICAM1 [plasma membrane] (Homo sapiens)
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (Homo sapiens)
ICAM1-5 bind Integrin alphaLbeta2 (LFA-1) (Homo sapiens)
ICAM 1-5 [plasma membrane] (Homo sapiens)
ICAM1 [plasma membrane] (Homo sapiens)
LFA-1:ICAM 1-5 [plasma membrane] (Homo sapiens)
ICAM 1-5 [plasma membrane] (Homo sapiens)
ICAM1 [plasma membrane] (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Interferon Signaling (Homo sapiens)
Interferon gamma signaling (Homo sapiens)
Expression of IFNG-stimulated genes (Homo sapiens)
IFN-gamma upregulated CAMs [plasma membrane] (Homo sapiens)
ICAM1 [plasma membrane] (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-10 signaling (Homo sapiens)
IL10 negatively regulates plasma membrane-associated inflammatory mediators (Homo sapiens)
IL10-downregulated plasma membrane proteins [plasma membrane] (Homo sapiens)
ICAM1 [plasma membrane] (Homo sapiens)
Interleukin-4 and Interleukin-13 signaling (Homo sapiens)
Expression of STAT3-upregulated plasma membrane proteins (Homo sapiens)
STAT3-upregulated plasma membrane proteins [plasma membrane] (Homo sapiens)
ICAM1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P05362 ICAM1
Gene Names
ICAM1
Chain
signal peptide:1-27, chain:28-532
Reference Genes
BioGPS Gene:3383 ICAM1
COSMIC (genes):ICAM1 ICAM1
CTD Gene:3383 ICAM1
dbSNP Gene:3383 ICAM1
ENSEMBL:ENSG00000090339 ICAM1
HGNC:5344 ICAM1
KEGG Gene (Homo sapiens):3383 ICAM1
Monarch:3383 ICAM1
NCBI Gene:3383 ICAM1
OMIM:147840 ICAM1
UCSC:P05362 ICAM1
Reference Transcript
RefSeq:NM_000201.2 ICAM1
Other Identifiers
0001690398
0004760026
11732999_a_at
11733000_at
11747499_a_at
16858137
16858148
202637_s_at
202638_s_at
215485_s_at
32640_at
3383
3820444
3820445
3820446
3820447
3820449
3820450
3820451
3820452
3820454
3820455
3820459
3820460
3820461
3820462
3820463
3820464
3820465
8025601
8025612
A_14_P107071
A_14_P134785
A_14_P200519
A_23_P130537
GE62810
GE82686
GO:0000003
GO:0000902
GO:0001541
GO:0001618
GO:0001666
GO:0001772
GO:0001910
GO:0001975
GO:0002291
GO:0002376
GO:0002438
GO:0002457
GO:0002693
GO:0003013
GO:0003674
GO:0004888
GO:0005178
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005886
GO:0005887
GO:0005925
GO:0006464
GO:0006810
GO:0006950
GO:0007010
GO:0007155
GO:0007157
GO:0007159
GO:0007165
GO:0007568
GO:0007569
GO:0007605
GO:0008150
GO:0008219
GO:0008360
GO:0009058
GO:0009897
GO:0009986
GO:0010212
GO:0010477
GO:0014070
GO:0016020
GO:0016021
GO:0016032
GO:0019221
GO:0022607
GO:0022614
GO:0030154
GO:0030198
GO:0030838
GO:0031012
GO:0031669
GO:0032496
GO:0032868
GO:0033627
GO:0034641
GO:0034698
GO:0038023
GO:0040011
GO:0042493
GO:0042592
GO:0043200
GO:0043226
GO:0043547
GO:0044403
GO:0044406
GO:0044877
GO:0045121
GO:0045429
GO:0045471
GO:0045907
GO:0046688
GO:0046718
GO:0046813
GO:0048856
GO:0048870
GO:0050731
GO:0050776
GO:0050877
GO:0050900
GO:0051092
GO:0051926
GO:0060333
GO:0061028
GO:0062023
GO:0065003
GO:0070062
GO:0070374
GO:0071222
GO:0071310
GO:0071312
GO:0071333
GO:0071346
GO:0071347
GO:0071354
GO:0071356
GO:0071456
GO:0071549
GO:0072683
GO:0090557
GO:0097368
GO:0098609
GO:1900027
GO:1902042
GO:1904646
GO:1904996
GO:1990830
GO:2000352
HMNXSV003023566
HMNXSV003043999
Hs.168383.0.A1_3p_a_at
Hs.168383.1.A1_3p_a_at
ILMN_1734660
ILMN_1812226
M24283_at
M55024_s_at
PH_hs_0024395
TC19000174.hg
TC19001977.hg
TC19001978.hg
g4557877_3p_a_at
Participates
as a member of
STAT3-upregulated plasma membrane proteins [plasma membrane] (Homo sapiens)
IL10-downregulated plasma membrane proteins [plasma membrane] (Homo sapiens)
IFN-gamma upregulated CAMs [plasma membrane] (Homo sapiens)
ICAM 1-5 [plasma membrane] (Homo sapiens)
Inferred To
si:ch211-66e2.3 [plasma membrane]
(Danio rerio)
si:ch73-208g10.1 [plasma membrane]
(Danio rerio)
ICAM1 [plasma membrane]
(Bos taurus)
ICAM1 [plasma membrane]
(Sus scrofa)
ICAM1 [plasma membrane]
(Xenopus tropicalis)
Icam1 [plasma membrane]
(Mus musculus)
Icam1 [plasma membrane]
(Rattus norvegicus)
icam3 [plasma membrane]
(Danio rerio)
si:ch211-74m13.1 [plasma membrane]
(Danio rerio)
Homologues of ICAM1 [plasma membrane]
(Danio rerio)
Homologues of ICAM1 [plasma membrane]
(Xenopus tropicalis)
sc:d0202 [plasma membrane]
(Danio rerio)
si:ch211-66e2.5 [plasma membrane]
(Danio rerio)
Cross References
RefSeq
NP_000192.2
ZINC - World Drugs
ICAM1_HUMAN
OpenTargets
ENSG00000090339
ZINC - FDA approved
ICAM1_HUMAN
ZINC - Substances
ICAM1_HUMAN
ZINC target
P05362
PRO
P05362
GlyGen
P05362
PDB
1IAM
,
1D3I
,
1Z7Z
,
7BG7
,
6S8U
,
1D3E
,
5MZA
,
6EIT
,
1MQ8
,
1P53
,
2OZ4
,
1D3L
,
1IC1
,
3TCX
ZINC - Investigational
ICAM1_HUMAN
GeneCards
P05362
HPA
ENSG00000090339-ICAM1
Ensembl
ENSP00000264832
,
ENSG00000090339
,
ENST00000264832
Pharos - Targets
P05362
ZINC - Predictions - Purchasable
ICAM1_HUMAN
Orphanet
28516
HMDB Protein
HMDBP02089
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