Reactome | KRTAP12-2 [cytosol]

KRTAP12-2 [cytosol]

Stable Identifier

R-HSA-6810271

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Keratin-associated protein 12-2, KR122_HUMAN

Locations in the PathwayBrowser

Expand all

Developmental Biology (Homo sapiens)

- Keratinization (Homo sapiens)
  - Formation of hair keratin fibres (Homo sapiens)
    - Keratin associated proteins [cytosol] (Homo sapiens)
      - KRTAP12s [cytosol] (Homo sapiens)
        
        KRTAP12-2 [cytosol] (Homo sapiens)
    - Keratin tonofilament:Keratin associated proteins polymer [cytosol] (Homo sapiens)
      - Keratin tonofilament, KAPs [cytosol] (Homo sapiens)
        
        Keratin associated proteins [cytosol] (Homo sapiens)
        
        KRTAP12s [cytosol] (Homo sapiens)
        
        KRTAP12-2 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:P59991 KRTAP12-2

Gene Names

KRTAP12-2, KAP12.2, KRTAP12.2

Chain

chain:1-146

Reference Genes

BioGPS Gene:353323 KRTAP12-2

COSMIC (genes):KRTAP12-2 KRTAP12-2

CTD Gene:353323 KRTAP12-2

dbSNP Gene:353323 KRTAP12-2

ENSEMBL:ENSG00000221864 KRTAP12-2

HGNC:20530 KRTAP12-2

KEGG:hsa:353323 KRTAP12-2

Monarch:353323 KRTAP12-2

NCBI Gene:353323 KRTAP12-2

UCSC:P59991 KRTAP12-2

Reference Transcript

RefSeq:NM_181684.3 KRTAP12-2

Other Identifiers

11735924_s_at

11742006_at

11742007_x_at

16926402

353323

3934624

3934625

3934626

3934627

3934628

3934629

3934630

8070791

A_24_P203284

A_33_P3354404

GO:0005515

GO:0005829

GO:0005882

HMNXSV003017724

ILMN_1697704

PH_hs_0034015

PH_hs_0037203

TC21000533.hg

Participates

as a member of

KRTAP12s [cytosol] (Homo sapiens)

Inferred To

LOC110256282 [cytosol] (Sus scrofa)

KRTAP12-2 [cytosol] (Bos taurus)

KRTAP12-2 [cytosol] (Canis familiaris)

LOC106508044 [cytosol] (Sus scrofa)

Krtap12-21 [cytosol] (Mus musculus)

Homologues of KRTAP12-2 [cytosol] (Bos taurus)

Homologues of KRTAP12-2 [cytosol] (Mus musculus)

Homologues of KRTAP12-2 [cytosol] (Sus scrofa)

Krtap12-20 [cytosol] (Mus musculus)

Krtap12-22 [cytosol] (Mus musculus)

Krtap12-1 [cytosol] (Mus musculus)

Cross References

RefSeq

NP_859012.1

ENSEMBL

ENSP00000354001, ENSG00000221864, ENST00000360770

OpenTargets

ENSG00000221864

GeneCards

KRTAP12-2

HPA

ENSG00000221864-KRTAP12-2

PRO

P59991

Pharos - Targets

P59991

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O95231 VENTX	1	VENTX [nucleoplasm] (R-HSA-8853887)	0.718	6
UniProt:O60565 GREM1	1	GREM1 [extracellular region] (R-HSA-9831023)	0.556	3
UniProt:P62877 RBX1	2	RBX1 [nucleoplasm] (R-HSA-1234142) RBX1 [cytosol] (R-HSA-180582)	0.556	3
UniProt:P0DPK4 NOTCH2NLC	1	NOTCH2NLC [extracellular region] (R-HSA-9908932)	0.556	3
UniProt:Q14498 RBM39	1	RBM39 [nucleoplasm] (R-HSA-9770254)	0.556	3
UniProt:Q86YT5 SLC13A5	1	SLC13A5 [plasma membrane] (R-HSA-433135)	0.556	3
UniProt:P49638 TTPA	1	TTPA [cytosol] (R-HSA-2980979)	0.556	3
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.556	3
UniProt:Q7Z3S9 NOTCH2NLA	3	NOTCH2NLA [extracellular region] (R-HSA-9908935) NOTCH2NLA(1-?) [extracellular region] (R-HSA-9911493) NOTCH2NLA(?-236) [extracellular region] (R-HSA-9911490)	0.556	3
UniProt:P25490 YY1	1	YY1 [nucleoplasm] (R-HSA-4086091)	0.556	3
UniProt:Q12837 POU4F2	1	POU4F2 [nucleoplasm] (R-HSA-6804414)	0.556	3
UniProt:O15160 POLR1C	2	POLR1C [cytosol] (R-HSA-1964454) POLR1C [nucleoplasm] (R-HSA-63498)	0.556	3

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