Reactome | RIPPLY2 [nucleoplasm]

RIPPLY2 [nucleoplasm]

Stable Identifier

R-HSA-9825566

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Protein ripply2, RIPP2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q5TAB7 RIPPLY2

Gene Names

RIPPLY2, C6orf159

Chain

chain:1-128

Reference Genes

BioGPS Gene:134701 RIPPLY2

COSMIC (genes):RIPPLY2 RIPPLY2

CTD Gene:134701 RIPPLY2

dbSNP Gene:134701 RIPPLY2

ENSEMBL:ENSG00000203877 RIPPLY2

HGNC:21390 RIPPLY2

Monarch:134701 RIPPLY2

NCBI Gene:134701 RIPPLY2

OMIM:609891 RIPPLY2

UCSC:Q5TAB7 RIPPLY2

Reference Transcript

RefSeq:NM_001009994.2 RIPPLY2

Other Identifiers

11732065_a_at

134701

17010708

236771_PM_at

236771_at

2915477

2915478

2915479

2915480

2915481

2915483

2915484

2915485

2915486

2915487

2915488

2915489

2915490

80555_at

8120937

A_32_P216566

GE523505

GO:0000122

GO:0001503

GO:0001756

GO:0005515

GO:0005634

GO:0006355

GO:0007219

GO:0007368

GO:0009798

GO:0009880

GO:0010468

GO:0032525

GO:0036342

GO:0043226

GO:0060349

HMNXSV003008097

HMNXSV003038578

Hs.149454.0.A1_3p_at

ILMN_2200915

PH_hs_0039710

TC06000773.hg

TC06002906.hg

Participates

as an output of

Expression of RIPPLY2 in presomitic mesoderm (Homo sapiens)

as a component of

TBX6:RIPPLY2:26S proteasome [nucleoplasm] (Homo sapiens)

as an input of

RIPPLY2 binds TBX6 and recruits the 26S proteasome (Homo sapiens)

Cross References

ENSEMBL

ENSP00000358701, ENSP00000358703, ENST00000369687, ENST00000369689

OpenTargets

ENSG00000203877

HPA

ENSG00000203877-RIPPLY2

PRO

Q5TAB7

Pharos - Targets

Q5TAB7

Orphanet

RIPPLY2

Interactors (16)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8N6L0 KASH5			0.795	8
UniProt:P40425 PBX2			0.631	5
UniProt:Q8NBJ4 GOLM1	2	p-GOLM1 [endoplasmic reticulum lumen] (R-HSA-8956938) GOLM1 [endoplasmic reticulum lumen] (R-HSA-8956710)	0.556	3
UniProt:P17568 NDUFB7	1	NDUFB7 [mitochondrial inner membrane] (R-HSA-59940)	0.556	3
UniProt:Q7Z699 SPRED1	2	SPRED1 [plasma membrane] (R-HSA-5658225) SPRED1 [cytosol] (R-HSA-5654207)	0.556	3
UniProt:Q5T686 AVPI1			0.556	3
UniProt:Q9BYU1 PBX4			0.556	5
UniProt:Q3SXR2 CC036			0.556	3
UniProt:Q05BK6 Q05BK6			0.556	3
UniProt:P26378-2 P263782			0.556	3
UniProt:Q8N205 SYNE4			0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	6
UniProt:Q04725 TLE2	2	Ub-TLE2 [nucleoplasm] (R-HSA-3322370) TLE2 [nucleoplasm] (R-HSA-212354)	0.527	3
UniProt:Q9Y2C4 EXOG	1	EXOG [mitochondrial matrix] (R-HSA-9914864)	0.527	2
UniProt:Q08117 TLE5	1	AES [nucleoplasm] (R-HSA-4648963)	0.527	3
UniProt:Q15654 TRIP6			0.527	3

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