RIPPLY2 binds TBX6 and recruits the 26S proteasome

Stable Identifier
R-HSA-9825555
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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RIPPLY2 binds TBX6 and recruits the 26S proteasome
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RIPPLY2 inhibits TBX6 activity post-translationally (inferred from mouse homologs) by binding TBX6 and recruiting the proteasome to degrade TBX6 (inferred from mouse homologs). TBX6 is ubiquitinated by an unknown mechanism prior to degradation (inferred from mouse homologs).
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Inferred From
Ripply2 binds Tbx6 and recruits the 26S proteasome (Mus musculus)
Authored
May, B  (2023-01-25)
Reviewed
Yamaguchi, TP  (2023-05-09)
Chalamalasetty, RB  (2023-05-09)
Created
May, B  (2023-01-26)
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