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SIX1 [nucleoplasm]
Stable Identifier
R-HSA-9757860
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Homeobox protein SIX1, Sine oculis homeobox homolog 1
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Kidney development (Homo sapiens)
Formation of the ureteric bud (Homo sapiens)
Expression of GREM1 in metanephric mesenchyme (Homo sapiens)
SIX1 [nucleoplasm] (Homo sapiens)
Expression of PAX2 in metanephric mesenchyme (Homo sapiens)
SIX1 [nucleoplasm] (Homo sapiens)
Expression of SALL1 in metanephric mesenchyme (Homo sapiens)
SIX1 [nucleoplasm] (Homo sapiens)
Expression of SIX1 in metanephric mesenchyme (Homo sapiens)
SIX1 [nucleoplasm] (Homo sapiens)
Expression of SIX2 in metanephric mesenchyme (Homo sapiens)
SIX1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q15475 SIX1
Gene Names
SIX1
Chain
chain:1-284
Reference Genes
BioGPS Gene:6495 SIX1
COSMIC (genes):SIX1 SIX1
CTD Gene:6495 SIX1
dbSNP Gene:6495 SIX1
ENSEMBL:ENSG00000126778 SIX1
ENSEMBL_homo_sapiens_GENE:ENSG00000126778.12 SIX1
HGNC:10887 SIX1
KEGG Gene (Homo sapiens):6495 SIX1
Monarch:6495 SIX1
NCBI Gene:6495 SIX1
OMIM:601205 SIX1
UCSC:Q15475 SIX1
Reference Transcript
RefSeq:NM_005982.3 SIX1
Other Identifiers
11724112_at
11724113_a_at
11758110_s_at
16793610
205817_PM_at
205817_at
228347_PM_at
228347_at
3567349
3567350
3567351
3567352
3567353
3567354
3567355
3567356
3567357
3567361
3567362
3567380
3567382
3567384
3567386
3567388
3567390
40004_at
62110_at
6495
72890_at
7979505
A_21_P0008445
A_23_P76914
GE80012
GO:0000122
GO:0000785
GO:0000976
GO:0000978
GO:0000981
GO:0001223
GO:0001228
GO:0001657
GO:0001658
GO:0001759
GO:0001822
GO:0002376
GO:0003151
GO:0003677
GO:0003682
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0005730
GO:0005737
GO:0006351
GO:0006355
GO:0006357
GO:0006915
GO:0007219
GO:0007389
GO:0007519
GO:0007605
GO:0008582
GO:0010467
GO:0010468
GO:0012501
GO:0014033
GO:0014842
GO:0014857
GO:0021610
GO:0022008
GO:0023052
GO:0030154
GO:0030855
GO:0030878
GO:0030910
GO:0032880
GO:0034330
GO:0034504
GO:0035909
GO:0042472
GO:0042474
GO:0043066
GO:0043226
GO:0043524
GO:0043565
GO:0043586
GO:0045664
GO:0045893
GO:0045944
GO:0048538
GO:0048665
GO:0048699
GO:0048701
GO:0048704
GO:0048705
GO:0048741
GO:0048839
GO:0048856
GO:0048870
GO:0050678
GO:0050877
GO:0051450
GO:0051451
GO:0060037
GO:0061055
GO:0061197
GO:0061551
GO:0071599
GO:0072075
GO:0072095
GO:0072107
GO:0072172
GO:0072193
GO:0072198
GO:0072513
GO:0086100
GO:0090103
GO:0090190
GO:0090336
GO:0140110
GO:1905243
GO:1990837
GO:2000288
GO:2000729
GO:2001014
HMNXSV003033912
HMNXSV003039515
Hs.41295.0.S1_3p_at
ILMN_1812702
PH_hs_0003560
TC14001188.hg
TC14002034.hg
TC14002035.hg
X91868_at
g5174680_3p_at
p19324
Participates
as an output of
Expression of SIX1 in metanephric mesenchyme (Homo sapiens)
This entity regulates
Positively
Expression of GREM1 in metanephric mesenchyme
(Homo sapiens)
Expression of PAX2 in metanephric mesenchyme
(Homo sapiens)
Expression of SIX2 in metanephric mesenchyme
(Homo sapiens)
Cross References
RefSeq
NP_005973.1
OpenTargets
ENSG00000126778
GeneCards
Q15475
HPA
ENSG00000126778-SIX1
Ensembl
ENST00000645694
,
ENSG00000126778
,
ENSP00000494686
PRO
Q15475
Pharos - Targets
Q15475
Orphanet
15295
PDB
4EGC
Interactors (16)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q99502 EYA1
2
p-EYA1 [nucleoplasm]
(R-HSA-5683951)
EYA1 [nucleoplasm]
(R-HSA-5683625)
0.742
5
UniProt:Q08117-2 TLE5
0.718
6
UniProt:O00167 EYA2
2
p-EYA2 [nucleoplasm]
(R-HSA-5683954)
EYA2 [nucleoplasm]
(R-HSA-5683621)
0.692
4
UniProt:O75409 HYPM
0.666
4
UniProt:O00167-1 EYA2
0.558
3
UniProt:O00167-2 EYA2
0.556
3
UniProt:Q04726-4 TLE3
0.556
3
UniProt:Q58EX7 PLEKHG4
1
PLEKHG4 [cytosol]
(R-HSA-9679579)
0.556
3
UniProt:Q04864-2 REL
0.556
3
UniProt:P78424 PO6F2
0.556
3
UniProt:Q08117 TLE5
1
AES [nucleoplasm]
(R-HSA-4648963)
0.556
3
UniProt:P12883 MYH7
0.527
2
UniProt:P11055 MYH3
1
MYH3 [cytosol]
(R-HSA-390560)
0.527
2
UniProt:Q2NKX8 ERCC6L
1
ERCC6L [cytosol]
(R-HSA-376250)
0.527
2
UniProt:Q9Y623 MYH4
0.527
2
UniProt:Q99750 MDFI
0.508
2
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