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p-EYA1 [nucleoplasm]
Stable Identifier
R-HSA-5683951
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
DNA Repair (Homo sapiens)
DNA Double-Strand Break Repair (Homo sapiens)
DNA Double Strand Break Response (Homo sapiens)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Homo sapiens)
ATM phosphorylates EYA1-4 (Homo sapiens)
p-EYA1-4 [nucleoplasm] (Homo sapiens)
p-EYA1 [nucleoplasm] (Homo sapiens)
EYA1-4 dephosphorylates tyrosine Y142 of H2AFX (Homo sapiens)
p-EYA1-4 [nucleoplasm] (Homo sapiens)
p-EYA1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q99502 EYA1
Gene Names
EYA1
Chain
chain:1-592
Reference Genes
BioGPS Gene:2138 EYA1
COSMIC (genes):EYA1 EYA1
CTD Gene:2138 EYA1
dbSNP Gene:2138 EYA1
ENSEMBL:ENSG00000104313 EYA1
HGNC:3519 EYA1
KEGG:hsa:2138 EYA1
Monarch:2138 EYA1
NCBI Gene:2138 EYA1
OMIM:601653 EYA1
UCSC:Q99502 EYA1
Reference Transcript
RefSeq:XM_017013206.1 EYA1
RefSeq:XM_017013212.1 EYA1
RefSeq:NM_001288574.1 EYA1
RefSeq:NM_172059.3 EYA1
RefSeq:NM_000503.5 EYA1
RefSeq:NM_001288575.1 EYA1
RefSeq:NM_172058.3 EYA1
RefSeq:NM_172060.3 EYA1
Other Identifiers
11733671_a_at
11741159_a_at
11741226_a_at
1569736_PM_at
1569736_at
17078134
17078164
2138
214608_PM_s_at
214608_s_at
3140057
3140058
3140059
3140060
3140064
3140066
3140067
3140068
3140069
3140070
3140074
3140079
3140083
3140085
3140094
3140095
3140096
3140101
3140103
3140104
3140105
3140106
3140107
3140109
3140115
3140117
3140118
3140119
3140120
3140121
3140122
3140123
3140124
3140137
3140146
3140151
3140152
3140153
3140154
3140160
3140165
3140166
3140167
3140168
3140169
3140170
3140171
3140173
3140174
3140177
3140179
37073_at
8151310
A_19_P00318025
A_19_P00318343
A_19_P00320265
A_19_P00320476
A_19_P00322060
A_19_P00322863
A_21_P0013542
A_23_P502363
A_33_P3216763
A_33_P3366667
A_33_P3368238
GE55122
GE80846
GE833579
GO:0001656
GO:0001657
GO:0001658
GO:0003151
GO:0003723
GO:0003824
GO:0004721
GO:0004722
GO:0004725
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0006281
GO:0006302
GO:0006325
GO:0006338
GO:0006355
GO:0007275
GO:0007389
GO:0007501
GO:0007605
GO:0009653
GO:0009887
GO:0010212
GO:0014706
GO:0016604
GO:0016787
GO:0016925
GO:0017018
GO:0030154
GO:0032991
GO:0032993
GO:0035909
GO:0042472
GO:0042473
GO:0042474
GO:0043226
GO:0045165
GO:0045664
GO:0045739
GO:0045893
GO:0045944
GO:0046872
GO:0048665
GO:0048704
GO:0048752
GO:0048856
GO:0050673
GO:0050679
GO:0050877
GO:0060037
GO:0071599
GO:0071600
GO:0072513
GO:0090103
GO:0097192
GO:0140096
GO:0140793
GO:2001240
HMNXSV003027149
HMNXSV003028678
HMNXSV003045517
Hs.94210.0.S2_3p_a_at
Hs2.399749.1.S1_3p_at
ILMN_1747207
ILMN_1807554
ILMN_2322874
PH_hs_0005167
TC08001316.hg
TC08002377.hg
Y10260_at
Participates
as a candidate of
p-EYA1-4 [nucleoplasm] (Homo sapiens)
Other forms of this molecule
EYA1 [nucleoplasm]
Inferred To
phospho-p-EYA1 [nucleoplasm]
(Bos taurus)
phospho-p-EYA1 [nucleoplasm]
(Caenorhabditis elegans)
phospho-p-EYA1 [nucleoplasm]
(Canis familiaris)
phospho-p-EYA1 [nucleoplasm]
(Drosophila melanogaster)
phospho-p-EYA1 [nucleoplasm]
(Gallus gallus)
phospho-p-EYA1 [nucleoplasm]
(Mus musculus)
phospho-p-EYA1 [nucleoplasm]
(Rattus norvegicus)
phospho-p-EYA1 [nucleoplasm]
(Sus scrofa)
Modified Residues
Name
phosphorylated residue at unknown position
PsiMod Name
phosphorylated residue [MOD:00696]
PsiMod Definition
A protein modification that effectively replaces a hydrogen atom with a phosphate group.
Cross References
RefSeq
NP_001275503.1
,
XP_016868701.1
,
NP_742055.1
,
NP_742056.1
,
NP_742057.1
,
XP_016868695.1
,
NP_001275504.1
,
NP_000494.2
OpenTargets
ENSG00000104313
ENSEMBL
ENSP00000494438
,
ENST00000388740
,
ENSP00000342626
,
ENSP00000373394
,
ENST00000388742
,
ENSP00000410176
,
ENSP00000373392
,
ENST00000340726
,
ENST00000645793
,
ENST00000419131
,
ENSP00000496255
,
ENST00000647540
HPA
ENSG00000104313-EYA1
PRO
Q99502
Pharos - Targets
Q99502
Orphanet
EYA1
HMDB Protein
HMDBP08720
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q15475 SIX1
1
SIX1 [nucleoplasm]
(R-HSA-9757860)
0.742
5
UniProt:Q9NPC8 SIX2
1
SIX2 [nucleoplasm]
(R-HSA-9831037)
0.643
3
UniProt:P43378 PTPN9
1
PTPN9 [nucleoplasm]
(R-HSA-9008907)
0.527
2
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