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PLEKHG4 [cytosol]
Stable Identifier
R-HSA-9679579
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Puratrophin-1 alternativeName: Pleckstrin homology domain-containing family G member 4, PRTPHN1
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
CDC42 GTPase cycle (Homo sapiens)
CDC42 GEFs activate CDC42 (Homo sapiens)
CDC42 GEFs [cytosol] (Homo sapiens)
PLEKHG4 [cytosol] (Homo sapiens)
RAC1 GTPase cycle (Homo sapiens)
RAC1 GEFs activate RAC1 (Homo sapiens)
RAC1 GEFs [cytosol] (Homo sapiens)
PLEKHG4 [cytosol] (Homo sapiens)
RAC1 binds effectors at the plasma membrane (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
PLEKHG4 [cytosol] (Homo sapiens)
RAC1:GTP:RAC1 effectors [plasma membrane] (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
PLEKHG4 [cytosol] (Homo sapiens)
RHOA GTPase cycle (Homo sapiens)
RHOA GEFs activate RHOA (Homo sapiens)
RHOA GEFs [cytosol] (Homo sapiens)
PLEKHG4 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q58EX7 PLEKHG4
Gene Names
PLEKHG4, PRTPHN1
Chain
chain:1-1191
Reference Genes
COSMIC (genes):PLEKHG4 Q58EX72
dbSNP Gene:25894 Q58EX72
ENSEMBL:ENSG00000196155 PLEKHG4
Participates
as a candidate of
RHOA GEFs [cytosol] (Homo sapiens)
RAC1 GEFs [cytosol] (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
as a member of
CDC42 GEFs [cytosol] (Homo sapiens)
Inferred To
Dmel\CG15611 [cytosol]
(Drosophila melanogaster)
Homologues of PLEKHG4 [cytosol]
(Drosophila melanogaster)
CG15612 [cytosol]
(Drosophila melanogaster)
trio [cytosol]
(Drosophila melanogaster)
Arhgef25 [cytosol]
(Mus musculus)
Arhgef25 [cytosol]
(Rattus norvegicus)
ARHGEF25 [cytosol]
(Bos taurus)
ARHGEF25 [cytosol]
(Canis familiaris)
ARHGEF25 [cytosol]
(Sus scrofa)
unc-73 [cytosol]
(Caenorhabditis elegans)
arhgef25 [cytosol]
(Xenopus tropicalis)
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P31273 HOXC8
1
HOXC8 [nucleoplasm]
(R-HSA-3222311)
0.556
3
UniProt:P20618 PSMB1
7
PSMB1 [cytosol]
(R-HSA-68738)
PSMB1 [nucleoplasm]
(R-HSA-174347)
PSMB1 [secretory granule lumen]
(R-HSA-6803287)
PSMB1 [extracellular region]
(R-HSA-6806477)
PSMB1 [ficolin-1-rich granule lumen]
(R-HSA-6803340)
pro-PSMB1 [cytosol]
(R-HSA-9908139)
PSMB1(1-28) [cytosol]
(R-HSA-9908143)
0.556
3
UniProt:Q15475 SIX1
1
SIX1 [nucleoplasm]
(R-HSA-9757860)
0.556
3
UniProt:Q6W0C5 DPPA3
2
DPPA3 [cytosol]
(R-HSA-9818458)
DPPA3 [nucleoplasm]
(R-HSA-9817479)
0.556
3
UniProt:Q13330 MTA1
2
MTA1 [nucleoplasm]
(R-HSA-3465550)
polySUMO2,3-K509-MTA1 [nucleoplasm]
(R-HSA-3465537)
0.556
3
UniProt:O75604 USP2
2
USP2 [cytosol]
(R-HSA-5212661)
USP2 [nucleoplasm]
(R-HSA-5689946)
0.556
3
UniProt:Q99633 PRPF18
1
PRPF18 [nucleoplasm]
(R-HSA-5688093)
0.556
3
UniProt:Q9NQ94 A1CF
1
A1CF [nucleoplasm]
(R-HSA-3211440)
0.556
3
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