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RPS27A(1-76) [late endosome lumen]
Stable Identifier
R-HSA-9660022
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
late endosome lumen
Synonyms
RPS27A, ubiquitin (RPS27A)
Locations in the PathwayBrowser
Expand all
Autophagy (Homo sapiens)
Late endosomal microautophagy (Homo sapiens)
Substrate translocates into late endosomal lumen (Homo sapiens)
PL:HSPA8:Autophagy substrate [late endosome lumen] (Homo sapiens)
HSPA8 bound autophagic substrates [late endosome lumen] (Homo sapiens)
Substrates for chaperone mediated autophagy [late endosome lumen] (Homo sapiens)
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6 [late endosome lumen] (Homo sapiens)
PolyUb-Misfolded Proteins:HDAC6 [late endosome lumen] (Homo sapiens)
PolyUb-Misfolded Proteins [late endosome lumen] (Homo sapiens)
Ub-misfolded nascent CFTR [late endosome lumen] (Homo sapiens)
Ub [late endosome lumen] (Homo sapiens)
RPS27A(1-76) [late endosome lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P62979 RPS27A
Gene Names
RPS27A, UBA80, UBCEP1
Chain
chain:1-76, chain:77-156
Reference Genes
BioGPS Gene:6233 RPS27A
COSMIC (genes):RPS27A RPS27A
CTD Gene:6233 RPS27A
dbSNP Gene:6233 RPS27A
ENSEMBL:ENSG00000143947.15 RPS27A
HGNC:10417 RPS27A
KEGG Gene (Homo sapiens):6233 RPS27A
Monarch:6233 RPS27A
NCBI Gene:6233 RPS27A
OMIM:191343 RPS27A
UCSC:P62979 RPS27A
Reference Transcript
RefSeq:NM_001177413.1 RPS27A
RefSeq:NM_001135592.2 RPS27A
RefSeq:NM_002954.5 RPS27A
Other Identifiers
11741791_at
11744329_x_at
17119982
18670232
18670234
18670235
18670237
18670241
18670243
18670244
200017_PM_at
200017_at
242214_PM_at
242214_at
2482925
2482928
2482929
2482930
2482932
2482933
2482937
2482940
2482941
2482942
34570_at
3694166
3694168
3694170
3694172
6233
7893392
7893455
7893919
7894376
7894813
7894844
7908407
8001782
8042052
83250_at
A_23_P79732
GE716822
GO:0002181
GO:0003723
GO:0003735
GO:0005198
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0005739
GO:0005741
GO:0005768
GO:0005783
GO:0005789
GO:0005829
GO:0005840
GO:0005886
GO:0006412
GO:0010008
GO:0015935
GO:0016020
GO:0016567
GO:0019941
GO:0022626
GO:0022627
GO:0030163
GO:0030666
GO:0031386
GO:0031410
GO:0031625
GO:0031982
GO:0036211
GO:0043226
GO:0046872
GO:0070062
GO:1990904
HMNXSV003033635
Hs.311640.0.A1_3p_at
Hs.328922.0.A1_3p_at
ILMN_2048326
S79522_at
TC01004921.hg
TC02000321.hg
g4506712_3p_at
g4506712_3p_x_at
Participates
as a member of
Ub [late endosome lumen] (Homo sapiens)
Other forms of this molecule
RPS27A(1-76) [endocytic vesicle membrane]
RPS27A(77-156) [nucleoplasm]
Ub-33-RPS27A(1-76) [mitochondrial outer membrane]
Ub-63-RPS27A(1-76) [mitochondrial outer membrane]
Ub-6-RPS27A(1-76) [mitochondrial outer membrane]
Ub-11-RPS27A(1-76) [mitochondrial outer membrane]
Ub-48-RPS27A(1-76) [mitochondrial outer membrane]
Ub-29-RPS27A(1-76) [mitochondrial outer membrane]
Ub-27-RPS27A(1-76) [mitochondrial outer membrane]
N6-glycyl-L-lysine-RPS27A(1-76) [cytosol]
adenylatedlG76-RPS27A(1-76) [nucleoplasm]
RPS27A [cytosol]
adenylatedlG76-RPS27A(1-76) [cytosol]
Ub-48-RPS27A(1-76) [endoplasmic reticulum membrane]
Ub-48-RPS27A(1-76) [lysosomal membrane]
Ub-48-RPS27A(1-76) [endocytic vesicle membrane]
RPS27A(1-76) [endosome membrane]
RPS27A(1-76) [plasma membrane]
Ub-29-RPS27A(1-76) [cytosol]
Ub-6-RPS27A(1-76) [cytosol]
Ub-33-RPS27A(1-76) [cytosol]
Ub-27-RPS27A(1-76) [cytosol]
M1-RPS27A(1-76) [cytosol]
RPS27A(77-156) [cytosol]
RPS27A(1-76) [endoplasmic reticulum membrane]
Ub-27-RPS27A(1-76) [nucleoplasm]
Ub-29-RPS27A(1-76) [nucleoplasm]
Ub-33-RPS27A(1-76) [nucleoplasm]
Ub-11-RPS27A(1-76) [nucleoplasm]
Ub-63-RPS27A(1-76) [endosome membrane]
Ub-63-RPS27A(1-76) [plasma membrane]
Ub-11-RPS27A(1-76) [cytosol]
Ub-48-RPS27A(1-76) [nucleoplasm]
RPS27A(1-76) [nucleoplasm]
Ub-63-RPS27A(1-76) [nucleoplasm]
Ub-6-RPS27A(1-76) [nucleoplasm]
Ub-48-RPS27A(1-76) [cytosol]
RPS27A(1-76) [cytosol]
RPS27A(1-76) [lysosomal lumen]
Ub-63-RPS27A(1-76) [cytosol]
Cross References
RefSeq
NP_001129064.1
,
NP_001170884.1
,
NP_002945.1
OpenTargets
ENSG00000143947
HPA
ENSG00000143947-RPS27A
GeneCards
P62979
Ensembl
ENST00000404735
,
ENSP00000272317
,
ENSP00000385659
,
ENST00000272317
,
ENST00000402285
,
ENSP00000383981
,
ENSG00000143947
PRO
P62979
Pharos - Targets
P62979
Orphanet
24875
PDB
6ZP4
,
2KHW
,
6OLI
,
5FLX
,
3NHE
,
6DC6
,
5LKS
,
3PHD
,
6ZMI
,
6ZON
,
3K9P
,
6ZVJ
,
7MQA
,
7WU0
,
3N30
,
6YBS
,
6KFP
,
6ZVH
,
2L0T
,
7WTX
,
3VDZ
,
7WTW
,
5AJ0
,
7QP7
,
4R62
,
6KIW
,
6ZN5
,
5WVO
,
6G5I
,
7JQC
,
6Z6L
,
2KWV
,
6Z6M
,
7OOJ
,
2KTF
,
6ZMO
,
6ZXH
,
3PHW
,
6ZXE
,
6OLF
,
6G51
,
3N32
,
4UG0
,
2KOX
,
6ZOJ
,
2XK5
,
7MQ9
,
6J99
,
6OM7
,
6ZXD
,
5T2C
,
6SQO
,
6ZLW
,
6KIV
,
6IP5
,
6OM0
,
3TBL
,
6KIU
,
7WTT
,
6OLG
,
7A09
,
5A2Q
,
6ZME
,
7WTZ
,
7BWD
,
6ZOL
,
6FEC
,
3AXC
,
6KG6
,
7TQL
,
7JQB
,
7QP6
,
6ZMT
,
6Z6N
,
7WTV
,
7WTU
,
6XA1
,
6ZMW
,
6QZP
,
6G5H
,
6ZXG
,
4V6X
,
6ZV6
,
7K5I
,
6OLE
,
3NS8
,
6Y0G
,
6G18
,
5YDK
,
3I3T
,
2L0F
,
6G53
,
6Y57
,
6ZUO
,
6ZXF
,
6IP6
,
6OLZ
,
3NOB
,
6SQS
,
6IP8
,
6ZM7
,
2KWU
,
6SQR
Interactors (17)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q15038 DAZP2
0.781
9
UniProt:Q9Y3C5 RNF11
0.666
4
UniProt:P63244 RACK1
1
GNB2L1 [cytosol]
(R-HSA-5626956)
0.607
3
UniProt:Q9UMX0 UBQLN1
1
UBQLN1 [cytosol]
(R-HSA-8866006)
0.556
3
UniProt:Q99732 LITAF
0.556
3
UniProt:Q9NRQ2 PLS4
0.556
3
UniProt:Q9UHD9 UBQLN2
1
UBQLN2 [cytosol]
(R-HSA-8866007)
0.556
3
UniProt:I6L9I8 I6L9I8
0.556
3
UniProt:Q8N3F0 MTURN
0.556
3
UniProt:P54725 RAD23A
1
RAD23A [nucleoplasm]
(R-HSA-5688076)
0.556
3
UniProt:Q96CS7 PKHB2
0.556
3
UniProt:Q92567-2 FAM168A
0.556
3
UniProt:Q6ICB0 DESI1
0.556
3
UniProt:Q13137 CACO2
0.556
3
UniProt:O76024 WFS1
3
WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956747)
p-WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956998)
WFS1 [endoplasmic reticulum membrane]
(R-HSA-535474)
0.556
3
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
6
UniProt:P04792 HSPB1
3
HSPB1 [cytosol]
(R-HSA-450563)
p-S15,S78,S82-HSP27 [cytosol]
(R-HSA-5218697)
p-S78,S82 HSPB1 [cytosol]
(R-HSA-5687009)
0.556
3
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