Reactome | UBAC1 [cytosol]

UBAC1 [cytosol]

Stable Identifier

R-HSA-8851644

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Ubiquitin-associated domain-containing protein 1, UBAC1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9BSL1 UBAC1

Gene Names

UBAC1, GBDR1, KPC2, UBADC1

Chain

chain:1-405

Reference Genes

BioGPS Gene:10422 UBAC1

COSMIC (genes):UBAC1 UBAC1

CTD Gene:10422 UBAC1

dbSNP Gene:10422 UBAC1

ENSEMBL:ENSG00000130560 UBAC1

HGNC:30221 UBAC1

KEGG:hsa:10422 UBAC1

Monarch:10422 UBAC1

NCBI Gene:10422 UBAC1

OMIM:608129 UBAC1

UCSC:Q9BSL1 UBAC1

Reference Transcript

RefSeq:NM_016172.2 UBAC1

Other Identifiers

10422

11732402_a_at

17099799

202151_PM_s_at

202151_s_at

3229598

3229599

3229600

3229601

3229603

3229604

3229605

3229606

3229608

3229610

3229611

3229612

3229613

3229614

3229615

3229616

3229617

3229621

3229622

3229625

3229626

38841_at

8165064

A_23_P60324

GE63003

GO:0000151

GO:0005515

GO:0005737

GO:0005794

GO:0005829

GO:0005886

GO:0016567

GO:0031593

GO:0043226

GO:0051604

GO:0070062

GO:0070628

HMNXSV003011456

ILMN_1807044

PH_hs_0000964

TC09001721.hg

g7705380_3p_a_at

Participates

as a candidate of

E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)

Inferred To

ubac1 [cytosol] (Xenopus tropicalis)

UBAC1 [cytosol] (Bos taurus)

UBAC1 [cytosol] (Canis familiaris)

UBAC1 [cytosol] (Gallus gallus)

UBAC1 [cytosol] (Sus scrofa)

Ubac1 [cytosol] (Mus musculus)

Ubac1 [cytosol] (Rattus norvegicus)

Kpc2 [cytosol] (Drosophila melanogaster)

Cross References

RefSeq

NP_057256.2

ENSEMBL

ENST00000371756, ENSP00000360821

OpenTargets

ENSG00000130560

HPA

ENSG00000130560-UBAC1

PRO

Q9BSL1

Pharos - Targets

Q9BSL1

GlyGen

Q9BSL1

PDB

2DAI

Interactors (15)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.742	26
UniProt:P0CG47 UBB	20	UBB(77-152) [endocytic vesicle membrane] (R-HSA-939253) UBB(1-76) [endocytic vesicle membrane] (R-HSA-939231) UBB(153-228) [endocytic vesicle membrane] (R-HSA-939171) Ub-33-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783023) Ub-109-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783008) Ub-185-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783046) Ub-215-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783002) Ub-63-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783148) Ub-139-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783012) Ub-158-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783162) Ub-6-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783014) Ub-82-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783015) Ub-163-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783025) Ub-87-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6782998) Ub-11-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783109) Ub-124-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783131) Ub-200-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783100) Ub-48-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783165) Ub-181-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783160) Ub-29-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783070)	0.742	5
UniProt:Q8TC12 RDH11	1	RDH11 [endoplasmic reticulum membrane] (R-HSA-975645)	0.589	2
UniProt:Q09327 MGAT3	1	MGAT3 [Golgi membrane] (R-HSA-975897)	0.556	3
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:P0CG48 UBC	20	UBC(381-456) [endocytic vesicle membrane] (R-HSA-939218) UBC(533-608) [endocytic vesicle membrane] (R-HSA-939220) UBC(609-684) [endocytic vesicle membrane] (R-HSA-939223) UBC(457-532) [endocytic vesicle membrane] (R-HSA-939195) UBC(153-228) [endocytic vesicle membrane] (R-HSA-939194) UBC(305-380) [endocytic vesicle membrane] (R-HSA-939228) UBC(229-304) [endocytic vesicle membrane] (R-HSA-939177) UBC(77-152) [endocytic vesicle membrane] (R-HSA-939210) UBC(1-76) [endocytic vesicle membrane] (R-HSA-939245) Ub-565-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783166) Ub-337-UBC(305-380) [mitochondrial outer membrane] (R-HSA-6783121) Ub-185-UBC(153-228) [mitochondrial outer membrane] (R-HSA-6783154) Ub-261-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783028) Ub-413-UBC(381-456) [mitochondrial outer membrane] (R-HSA-6783061) Ub-109-UBC(77-152) [mitochondrial outer membrane] (R-HSA-6783158) Ub-641-UBC(609-684) [mitochondrial outer membrane] (R-HSA-6783182) Ub-33-UBC(1-76) [mitochondrial outer membrane] (R-HSA-6783073) Ub-489-UBC(457-532) [mitochondrial outer membrane] (R-HSA-6783078) Ub-291-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783193) Ub-595-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783130)	0.556	3
UniProt:P24592 IGFBP6	1	IGFBP6 [extracellular region] (R-HSA-381475)	0.556	3
UniProt:Q9NWF9 RNF216	1	RNF216 [cytosol] (R-HSA-936043)	0.556	3
UniProt:P37840 SNCA	5	SNCA [cytosol] (R-HSA-5658500) p-S129-SNCA [cytosol] (R-HSA-9836432) Ub-SNCA [cytosol] (R-HSA-5660754) SNCA [extracellular region] (R-HSA-976954) SNCA A30P [cytosol] (R-HSA-5658569)	0.556	3
UniProt:O60294 LCMT2	1	LCMT2 [cytoplasm] (R-HSA-6782869)	0.527	2
UniProt:P13501 CCL5	1	CCL5(24-91) [extracellular region] (R-HSA-373108)	0.527	2
UniProt:Q8WXG1 RSAD2	1	RSAD2 [endoplasmic reticulum membrane] (R-HSA-5624199)	0.527	2
UniProt:Q9BQ52 ELAC2	3	ELAC2 [mitochondrial matrix] (R-HSA-6786837) ELAC2 [nucleoplasm] (R-HSA-5696766) ELAC2 [cytosol] (R-HSA-9708824)	0.527	3
UniProt:P62979 RPS27A	20	RPS27A(1-76) [endocytic vesicle membrane] (R-HSA-939208) RPS27A(77-156) [nucleoplasm] (R-HSA-6798734) Ub-33-RPS27A(1-76) [mitochondrial outer membrane] (R-HSA-6783024) Ub-63-RPS27A(1-76) [mitochondrial outer membrane] (R-HSA-6783200) Ub-6-RPS27A(1-76) [mitochondrial outer membrane] (R-HSA-6783040) Ub-11-RPS27A(1-76) [mitochondrial outer membrane] (R-HSA-6783085) Ub-48-RPS27A(1-76) [mitochondrial outer membrane] (R-HSA-6783075) Ub-29-RPS27A(1-76) [mitochondrial outer membrane] (R-HSA-6783146) Ub-63-RPS27A(1-76) [cytosol] (R-HSA-939248) RPS27A(1-76) [lysosomal lumen] (R-HSA-9660001) RPS27A(1-76) [cytosol] (R-HSA-939205) p-S65-RPS27A(1-76) [mitochondrial outer membrane] (R-HSA-9834951) Ub-48-RPS27A(1-76) [cytosol] (R-HSA-939202) RPS27A(1-76) [mitochondrial outer membrane] (R-HSA-9834993) RPS27A(1-76) [late endosome lumen] (R-HSA-9660022) Ub-6-RPS27A(1-76) [nucleoplasm] (R-HSA-6782608) Ub-63-RPS27A(1-76) [nucleoplasm] (R-HSA-6782503) Ub-48-RPS27A(1-76) [nucleoplasm] (R-HSA-5683037) RPS27A(1-76) [nucleoplasm] (R-HSA-939849) Ub-11-RPS27A(1-76) [cytosol] (R-HSA-3095933)	0.527	2
UniProt:P51572 BCAP31	6	BCAP31 [lumenal side of endoplasmic reticulum membrane] (R-HSA-985503) BCAP31 [endoplasmic reticulum membrane] (R-HSA-9714333) BCAP31(2-245) [endoplasmic reticulum membrane] (R-HSA-201587) BCAP31(165-237) [endoplasmic reticulum membrane] (R-HSA-351909) BCAP31(2-164) [endoplasmic reticulum membrane] (R-HSA-351826) BCAP31(238-246) [cytosol] (R-HSA-351912)	0.527	2

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