Reactome | SYCE1 [nucleoplasm]

SYCE1 [nucleoplasm]

Stable Identifier

R-HSA-912456

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Synaptonemal complex central element protein 1, SYCE1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q8N0S2 SYCE1

Gene Names

SYCE1, C10orf94

Chain

chain:1-351

Reference Genes

BioGPS Gene:93426 SYCE1

COSMIC (genes):SYCE1 SYCE1

CTD Gene:93426 SYCE1

dbSNP Gene:93426 SYCE1

ENSEMBL:ENSG00000171772 SYCE1

ENSEMBL_homo_sapiens_GENE:ENSG00000171772.17 SYCE1

HGNC:28852 SYCE1

KEGG Gene (Homo sapiens):93426 SYCE1

Monarch:93426 SYCE1

NCBI Gene:93426 SYCE1

OMIM:611486 SYCE1

UCSC:Q8N0S2 SYCE1

Reference Transcript

Other Identifiers

11734248_a_at

11740727_a_at

1554675_3p_a_at

1554675_PM_a_at

1554675_a_at

16719910

233084_PM_s_at

233084_s_at

3315343

3315344

3315345

3315346

3315348

3315349

3315350

3315351

3315352

3315353

3315354

3315355

3315356

3315357

3315358

3315360

3315364

3315365

3315370

3315383

3315384

3315389

3669436

56494_at

7937230

7937247

93426

GO:0000228

GO:0000795

GO:0000801

GO:0005515

GO:0005634

GO:0005694

GO:0007049

GO:0007059

GO:0007130

GO:0022414

GO:0043226

GO:0051301

GO:0051321

GO:0070193

GO:0140013

HMNXSV003036877

Hs.117226.1.S1_3p_a_at

Hs2.117226.2.S1_3p_at

Hs2.117226.2.S1_3p_s_at

Hs2.117226.2.S1_3p_x_at

ILMN_1732189

ILMN_1773168

PH_hs_0032626

TC10002956.hg

Participates

as a component of

Central Element of Synaptonemal Complex [nucleoplasm] (Homo sapiens)

as an input of

Synapsis (Homo sapiens)

Cross References

RefSeq

NP_570140.1, NP_001137235.1

OpenTargets

ENSG00000171772

HPA

ENSG00000171772-SYCE1

GeneCards

Q8N0S2

Ensembl

ENSP00000357503, ENST00000343131, ENSP00000341282, ENST00000368517, ENSG00000171772

PRO

Q8N0S2

Pharos - Targets

Q8N0S2

Orphanet

23068

Interactors (56)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13515 BFSP2			0.805	11
UniProt:P06753 TPM3	3	TPM3 [cytosol] (R-HSA-390543) TPM3(2-258)insV-p-7Y-ALK(1059-1620) fusion [cytosol] (R-HSA-9710837) TPM3(2-258)insV-ALK(1059-1620) fusion [cytosol] (R-HSA-9710848)	0.735	7
UniProt:P09917 ALOX5	6	p-S272-ALOX5 [cytosol] (R-HSA-265276) ALOX5 [secretory granule lumen] (R-HSA-6801306) ALOX5 [extracellular region] (R-HSA-6806468) ALOX5 [ficolin-1-rich granule lumen] (R-HSA-6801302) ALOX5 [cytosol] (R-HSA-429010) p-S272-ALOX5 [nuclear envelope] (R-HSA-2318765)	0.718	6
UniProt:Q9Y5B8 NME7	1	NME7 [cytosol] (R-HSA-6806880)	0.718	6
UniProt:Q99816 TSG101	1	TSG101 [endosome membrane] (R-HSA-2980549)	0.718	6
UniProt:Q8NA61-2 CBY2			0.696	7
UniProt:Q9UJC3 HOOK1			0.666	4
UniProt:P09493 TPM1	1	TPM1 [cytosol] (R-HSA-390547)	0.666	4
UniProt:Q9Y3C0 WASC3			0.666	4
UniProt:O43739 CYTH3	2	CYTH3 [cytosol] (R-HSA-8847834) CYTH3 [Golgi membrane] (R-HSA-8847833)	0.666	4
UniProt:P09493-10 TPM1			0.601	4
UniProt:Q96MY7 F161B			0.601	4
UniProt:B5MC10 B5MC10			0.601	4
UniProt:Q8IYI6 EXOC8	2	EXOC8 [plasma membrane] (R-HSA-264948) EXOC8 [cytosol] (R-HSA-5623388)	0.556	3
UniProt:Q9UBY9 HSPB7			0.556	3
UniProt:Q3B820 F161A			0.556	3
UniProt:Q99757 TXN2	2	TXN2 [mitochondrial matrix] (R-HSA-3323048) 2xHC-TXN2 [mitochondrial matrix] (R-HSA-3323059)	0.556	3
UniProt:Q96BD8 SKA1	1	SKA1 [cytosol] (R-HSA-376228)	0.556	3
UniProt:Q8TD31-3 CCHCR1			0.556	3
UniProt:O95983-2 MBD3			0.556	3
UniProt:Q96HT8 MR1L1			0.556	3
UniProt:Q969G3 SMARCE1	1	SMARCE1 [nucleoplasm] (R-HSA-389258)	0.556	3
UniProt:P05783 KRT18	1	KRT18 [cytosol] (R-HSA-201582)	0.556	3
UniProt:Q96CS2 HAUS1	1	HAUS1 [cytosol] (R-HSA-8855199)	0.556	3
UniProt:Q15311 RALBP1	1	RALBP1 [cytosol] (R-HSA-195194)	0.556	3
UniProt:Q494V2-2 CFAP100			0.556	3
UniProt:Q16385 SSX2			0.556	3
UniProt:Q3B7T1-5 EDRF1			0.556	3
UniProt:Q68D86 C102B			0.556	3
UniProt:Q9BW66 CINP			0.556	3
UniProt:Q9BXY8 BEX2			0.556	3
UniProt:Q06455-2 RUNX1T1			0.556	3
UniProt:P0DTD1-PRO_0000449633 REP			0.556	3
UniProt:Q9BWG6 SCNM1			0.556	3
UniProt:Q9H0A9-2 SPATC1L			0.556	3
UniProt:P02545-2 LMNA	5	LMNA-2 [nuclear envelope] (R-HSA-912378) p-S22, S395-LMNA-2 [nucleoplasm] (R-HSA-5229019) p-S395-LMNA-2 [nucleoplasm] (R-HSA-5228740) Lamin C [nucleoplasm] (R-HSA-264872) LMNA-2 [cytosol] (R-HSA-2995387)	0.556	3
UniProt:Q8N4C7 STX19			0.556	3
UniProt:Q06543 GPN3			0.556	3
UniProt:Q8NA54 IQUB			0.556	3
UniProt:A0A0S2Z528 A0A0S2Z528			0.556	3
UniProt:Q15973 ZNF124	1	ZNF124 [nucleoplasm] (R-HSA-975017)	0.556	3
UniProt:P38340 NTM1			0.556	3
UniProt:Q5VU62 Q5VU62			0.556	3
UniProt:Q9BVG8 KIFC3			0.556	3
UniProt:Q8WV44 TRIM41	1	TRIM41 [cytosol] (R-HSA-5688975)	0.556	3
UniProt:P15807 MET8			0.556	3
UniProt:Q8NA61 CBY2			0.556	3
UniProt:P09493-5 TPM1			0.556	3
UniProt:Q9BRG1 VPS25	1	VPS25 [cytosol] (R-HSA-917697)	0.556	3
UniProt:Q86WA8 LONP2	3	LONP2 [cytosol] (R-HSA-391291) LONP2 [peroxisomal matrix] (R-HSA-9033144) LONP2 [cytosol] (R-HSA-8963025)	0.556	3
UniProt:Q13077 TRAF1	3	TRAF1 [cytosol] (R-HSA-5634163) TRAF1(1-163) [cytosol] (R-HSA-5634199) TRAF1(164-416) [cytosol] (R-HSA-5634204)	0.556	3
UniProt:Q92993 KAT5	1	KAT5 [nucleoplasm] (R-HSA-3321979)	0.556	3
UniProt:Q9BYM8 RBCK1	1	RBCK1 [cytosol] (R-HSA-976018)	0.556	3
UniProt:Q9P0W2 HMG20B	1	HMG20B [nucleoplasm] (R-HSA-996745)	0.556	3
UniProt:P51911 CNN1			0.488	2
UniProt:Q9UBB9 TFIP11	1	TFIP11 [nucleoplasm] (R-HSA-8869310)	0.488	2

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