Synapsis

Stable Identifier
R-HSA-912505
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Formation of Central Elements of the Synaptonemal Complex
ReviewStatus
5/5
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Synapsis
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Initiation of recombination precedes and is required for synapsis (Roig et al. 2004). The synaptonemal complex forms when transverse filaments of SYCP1 link axial/lateral elements of sister chromatids to a central element comprising SYCE1, SYCE2, and other proteins (Tarsounas et al. 1997). The order of assembly is unknown.
Literature References
PubMed ID Title Journal Year
15235794 Female-specific features of recombinational double-stranded DNA repair in relation to synapsis and telomere dynamics in human oocytes

Roig, I, Liebe, B, Egozcue, J, Cabero, L, Garcia, M, Scherthan, H

Chromosoma 2004
9285814 Protein-protein interactions in the synaptonemal complex

Tarsounas, M, Pearlman, RE, Gasser, PJ, Park, MS, Moens, PB

Mol Biol Cell 1997
Participants
Input
Output
Participates
as an event of
Inferred From
Synapsis (Mus musculus)
Authored
May, B  (2010-07-03)
Reviewed
Bolcun-Filas, E  (2011-02-25)
Cohen, PE  (2011-02-05)
Holloway, JK  (2011-02-05)
Lyndaker, A  (2011-02-25)
Schimenti, JC  (2011-02-05)
Strong, E  (2011-02-25)
Created
May, B  (2010-07-09)
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