Reactome | SUN1 [nuclear envelope]

SUN1 [nuclear envelope]

Stable Identifier

R-HSA-912371

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nuclear envelope

Synonyms

SUN domain-containing protein 1, SUN1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O94901 SUN1

Gene Names

SUN1, KIAA0810, UNC84A

Chain

chain:1-785

Reference Genes

BioGPS Gene:23353 SUN1

COSMIC (genes):SUN1 SUN1

CTD Gene:23353 SUN1

dbSNP Gene:23353 SUN1

ENSEMBL:ENSG00000164828 SUN1

HGNC:18587 SUN1

KEGG:hsa:23353 SUN1

Monarch:23353 SUN1

NCBI Gene:23353 SUN1

OMIM:607723 SUN1

UCSC:O94901 SUN1

Reference Transcript

Other Identifiers

11717989_a_at

11721834_a_at

11747675_a_at

11753242_x_at

11756851_a_at

11757547_a_at

11762890_s_at

11763328_a_at

17042759

17042805

206487_PM_at

206487_at

212074_PM_at

212074_at

214169_3p_at

214169_PM_at

214169_at

223811_PM_s_at

223811_s_at

224808_PM_s_at

224808_s_at

230210_PM_at

230210_at

23353

2986725

2986827

2986828

2986829

2986830

2986832

2986833

2986834

2986835

2986836

2986838

2986839

2986840

2986841

2986842

2986843

2986844

2986845

2986846

2986847

2986848

2986849

2986850

2986851

2986852

2986853

2986854

2986855

2986856

2986857

2986858

2986859

2986860

2986861

2986862

2986863

2986864

2986865

2986866

2986867

2986868

2986869

2986870

2986871

2986872

2986873

2986874

2986876

2986878

2986879

2986880

2986881

2986882

2986884

2986885

2986886

2986888

2986889

2986890

2986892

2986914

2986915

2986916

2986919

2986920

2986923

2986925

2986927

2986928

2986929

2986930

36588_at

49144_at

51052_at

8131013

8131042

8131044

87078_at

A_23_P147070

A_23_P169838

A_23_P42836

A_24_P320645

A_24_P400355

A_33_P3276308

A_33_P3369663

GE53505

GE56575

GE83110

GE85087

GO:0000781

GO:0001503

GO:0005515

GO:0005521

GO:0005634

GO:0005635

GO:0005637

GO:0005737

GO:0007018

GO:0007129

GO:0007283

GO:0009612

GO:0016020

GO:0021817

GO:0022414

GO:0030154

GO:0031965

GO:0034993

GO:0042802

GO:0043226

GO:0043231

GO:0043495

GO:0051321

GO:0051642

GO:0060090

GO:0070197

GO:0090292

GO:0140444

HMNXSV003007660

HMNXSV003044292

HMNXSV003048277

Hs.107387.1.S2_3p_at

Hs.7531.1.S1_3p_a_at

Hs.7531.1.S1_3p_at

Hs.7531.2.S1_3p_at

Hs.7531.3.S1_3p_at

ILMN_1653437

ILMN_1701724

ILMN_1772316

PH_hs_0025654

PH_hs_0031513

PH_hs_0040985

TC07003316.hg

g13097677_3p_a_at

g13435158_3p_at

Participates

as a component of

Telomere Attachment Plate [nuclear envelope] (Homo sapiens)

as an input of

Telomeres cluster at the nuclear membrane (Homo sapiens)

Cross References

OpenTargets

ENSG00000164828

ENSEMBL

ENSP00000384015, ENSP00000392309, ENST00000401592, ENST00000389574, ENSP00000395952, ENST00000403868, ENSP00000374225, ENST00000457378, ENST00000425407, ENSP00000383947

HPA

ENSG00000164828-SUN1

PRO

O94901

Pharos - Targets

O94901

GlyGen

O94901

PDB

6R2I, 6R16, 6R15, 7E34, 8B5X, 7Z8Y, 8B46, 8AU0

Interactors (21)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8NF91 SYNE1	1	SYNE1 [nuclear envelope] (R-HSA-912352)	0.71	6
UniProt:Q8N205 SYNE4			0.655	7
UniProt:Q8N6L0 KASH5			0.618	5
UniProt:Q12912 IRAG2	2	LRMP [plasma membrane] (R-HSA-6806272) LRMP [azurophil granule membrane] (R-HSA-6799215)	0.618	6
UniProt:O94901 SUN1	1	SUN1 [nuclear envelope] (R-HSA-912371)	0.609	3
UniProt:P02545 LMNA	3	LMNA(1-567)-p-RAF1(279-648) fusion [cytosol] (R-HSA-6802537) LMNA(1-567)-RAF1(279-648) fusion [cytosol] (R-HSA-6802399) LMNA(1-646) [nuclear envelope] (R-HSA-535479)	0.564	2
UniProt:Q9NVF7 FBX28			0.527	2
UniProt:Q15654 TRIP6			0.527	2
UniProt:Q8WWF5 ZNRF4			0.527	2
UniProt:Q9Y6Q1 CAPN6	1	CAPN6 [cytosol] (R-HSA-8848635)	0.527	2
UniProt:Q8TCN5 ZN507			0.527	2
UniProt:Q9BQ31 KCNS3	1	KCNS3 [plasma membrane] (R-HSA-381709)	0.527	2
UniProt:Q8N6G5 CSGALNACT2	1	CSGALNACT2 [Golgi membrane] (R-HSA-1971506)	0.527	3
UniProt:Q401N2 ZACN			0.527	2
UniProt:P16444 DPEP1	1	DPEP1 [plasma membrane] (R-HSA-2142820)	0.527	3
UniProt:Q86UE6 LRRTM1	1	LRRTM1 [plasma membrane] (R-HSA-6797964)	0.527	2
UniProt:A2RUC4 TYW5	1	TYW5 [cytoplasm] (R-HSA-6783500)	0.527	2
UniProt:Q8WXH0-1 SYNE2			0.524	2
UniProt:Q8NF91-1 SYNE1			0.524	2
UniProt:P50402 EMD	4	EMD [nuclear envelope] (R-HSA-201573) EMD [cytosol] (R-HSA-9613988) EMD [endoplasmic reticulum membrane] (R-HSA-9613998) EMD [endosome membrane] (R-HSA-9715092)	0.463	2
UniProt:P04578 env	7	ENV [viral envelope] (R-HIV-173439) Surface protein gp120 [viral envelope] (R-HIV-171211) Transmembrane protein gp41 [viral envelope] (R-HIV-171195) Envelope glycoprotein gp160 [endoplasmic reticulum membrane] (R-HIV-189343) Glycosylated Envelope glycoprotein gp160 [Golgi membrane] (R-HIV-3149443) Transmembrane protein gp41 (P04578) [cytosol] (R-HIV-189359) Surface protein gp120 (P04578) [cytosol] (R-HIV-189269)	0.462	3