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TYW5 [cytoplasm]
Stable Identifier
R-HSA-6783500
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytoplasm
Synonyms
tRNA wybutosine-synthesizing protein 5, TYW5_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
tRNA processing (Homo sapiens)
tRNA modification in the nucleus and cytosol (Homo sapiens)
Synthesis of wybutosine at G37 of tRNA(Phe) (Homo sapiens)
TYW5 hydroxylates yW-72 yielding OHyW-72 at nucleotide 37 of tRNA(Phe) (Homo sapiens)
TYW5:Fe2+ dimer [cytoplasm] (Homo sapiens)
TYW5:Fe2+ [cytoplasm] (Homo sapiens)
TYW5 [cytoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:A2RUC4 TYW5
Gene Names
TYW5, C2orf60
Chain
chain:1-315
Reference Genes
BioGPS Gene:129450 TYW5
COSMIC (genes):TYW5 TYW5
CTD Gene:129450 TYW5
dbSNP Gene:129450 TYW5
ENSEMBL:ENSG00000162971 TYW5
ENSEMBL_homo_sapiens_GENE:ENSG00000162971.11 TYW5
HGNC:26754 TYW5
KEGG Gene (Homo sapiens):129450 TYW5
Monarch:129450 TYW5
NCBI Gene:129450 TYW5
OMIM:619882 TYW5
UCSC:A2RUC4 TYW5
Reference Transcript
RefSeq:NM_001039693.2 TYW5
Other Identifiers
11732419_a_at
11732420_at
11746531_a_at
129450
16907087
235181_PM_at
235181_at
235686_PM_at
235686_at
241825_PM_at
241825_at
2594312
2594314
2594315
2594316
2594317
2594318
2594319
2594322
2594323
2594327
2594331
2594335
2594342
2594346
43086_at
43667_at
45669_at
63226_at
8058108
91269_at
91424_at
A_23_P314691
A_24_P20139
A_32_P145968
A_32_P36942
GE519107
GO:0000049
GO:0003723
GO:0003824
GO:0005506
GO:0005737
GO:0006399
GO:0008033
GO:0016491
GO:0016706
GO:0031591
GO:0042803
GO:0046872
GO:0051213
GO:0102524
GO:0140098
GO:1901135
HMNXSV003034124
Hs.204619.0.A1_3p_at
Hs.295850.0.A1_3p_at
Hs.295850.1.A1_3p_at
ILMN_1785955
PH_hs_0023029
TC02002659.hg
TC02004772.hg
Participates
as a component of
TYW5:Fe2+ [cytoplasm] (Homo sapiens)
Cross References
RefSeq
NP_001034782.1
OpenTargets
ENSG00000162971
GeneCards
A2RUC4
HPA
ENSG00000162971-TYW5
Ensembl
ENSG00000162971
,
ENST00000354611
,
ENSP00000346627
PRO
A2RUC4
Pharos - Targets
A2RUC4
PDB
3AL5
,
3AL6
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O94901 SUN1
1
SUN1 [nuclear envelope]
(R-HSA-912371)
0.527
2
UniProt:Q9NZ43 USE1
1
USE1 [endoplasmic reticulum membrane]
(R-HSA-2193119)
0.527
2
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